PURPOSE Measurement of IgE specific to purified house dust mite (HDM) allergens may improve allergy diagnosis. This study aimed to investigate the sensitization profiles of Korean HDM allergic subjects suffering from respiratory allergy and atopic dermatitis (AD) to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20. METHODS Recombinant HDM allergens were produced in Pichia pastoris (...

House dust mite (HDM) allergen exposure is the most important cause of perennial allergic rhinitis and/or asthma. Although allergen-specific immunotherapy (AIT) with HDM is well established, published studies have been characterized by substantial heterogeneity in clinical endpoints. Standardization in measuring clinical efficacy is required. Moreover, when designing an AIT trial with HDM aller...

Method Retrospective chart review of patients evaluated for allergic rhinitis and underwent skin prick testing. A cohort of 250 patients was randomly selected with inclusion criteria being symptomatic allergic rhinitis and positive allergy skin prick testing to usual panel of allergens. Data collection included demographics, smoking exposure, symptom pattern, presence or absence of non-nasal sy...

BACKGROUND Children with asthma have a high prevalence of environmental allergies, especially to indoor allergens. The relationships of exposure to indoor allergens (dust mites, cat, dog, cockroach, and molds) and other host factors to allergy sensitization have not been evaluated simultaneously in a large cohort. OBJECTIVES We studied 1041 children aged 5 to 12 years with mild-to-moderate as...

House dust mites are widely distributed in the human habitat and work environment and produce very powerful allergens. The most important allergy-causing mites found in homes worldwide are the house dust mites Dermatophagoides farinae and D. pteronyssinus and the storage mite Blomia tropicalis. It is important to know which mite species are present in a geographical area when performing diagnos...

INTRODUCTION Specific immunotherapy has shown to be very useful for allergy control in dogs, with a common success rate ranging from 65% to 70%. However, this efficacy could probably be improved and the identification of individual allergomes, with the choice of more adequate molecular allergen pools for specific immunotherapy, being the strategy. AIM To map Dermatophagoides pteronyssinus (De...

various cross-sectional and longitudinal studies have suggested that synthetic bedding is associated with asthma, allergic rhinitis and eczema while feather bedding seems to be protective. synthetic bedding items have higher house dust mite allergen levels than feather bedding items. this is possibly the mechanism involved although fungal and bacterial proinflammatory compounds and volatile org...