purpose:  to determine the safety and efficacy of mitomycin-c injection into the lacrimal duct for treatment of partial nasolacrimal duct obstruction in adults. method: this is a before-after clinical trial performed on 20 patients with partial primary acquired nasolacrimal duct obstruction. we injected 1.5 ml of mitomycin-c 0.2 mg/ml into the lacrimal duct and repeated it with concentration of...

PURPOSE Electrochemotherapy is widely performed to treat solid tumors but experience with bladder cancer is limited. We investigated mitomycin C and cisplatin administered with electrochemotherapy for bladder cancer in vitro and in vivo. MATERIALS AND METHODS The human bladder cancer cell line SW780 was used. Cells were treated with electroporation, drug alone or electroporation plus increasi...

This study aims to provide information about the effect of Mitomycin C on contracted sockets surgery so that can inhibit migration fibroblast and synthesis collagen thus causing reduce fibrosis in vitro vivo a significant reduction scarring. The literature used is last 10 years 2021. Literature searches were from Science Direct, PubMed, Google Scholar electronic databases. initial stage obtaine...

Mouse L-cells were grown in suspension culture and exposed to varying concentrations, from 0.2 to 4 ¿ig/ml,of mitomycin C for periods ranging from 0.5 to 3.5 hr. A plot of cell colony-forming ability versus concentration of mitomycin C for different times of exposure yielded a series of exponential survival curves which were related by the fact that the product of the time of exposure and the ...

AIMS To evaluate the long term results of intraoperative mitomycin C application in dacryocystorhinostomy (DCR) surgery compared with results of the conventional procedure. METHODS In this prospective randomised controlled study, a total of 88 eyes diagnosed with acquired nasolacrimal duct obstruction were randomly divided into a conventional DCR group and a mitomycin C group in which mitomyc...

OBJECTIVE To create and test a slow-release antifibrotic drug-coated glaucoma drainage device using in vitro and in vivo experiments. METHODS A slow-release device incorporating mitomycin C in poly(2-hydroxyethyl methacrylate) disks was developed using redox-polymerization techniques. A standardized preparation of this drug delivery device was attached to the Ahmed glaucoma valve (model FP7; ...

cytomorphological changes of mitomycin c on urothelial cells may be misinterpreted as a neoplastic process. a 60-year old male patient who was given an eight-week course of intravesical mitomycin c due to non-invasive low grade transitional cell carcinoma. during his follow-up care, the findings of a urine cytology exam were as follows: nuclear enlargement of cells, wrinkled nuclear membranes, ...