نتایج جستجو برای: mmp20

تعداد نتایج: 76  

Journal: :Head & Face Medicine 2007
Maria CLG Santos P Suzanne Hart Mukundhan Ramaswami Cláudia M Kanno Thomas C Hart Sergio RP Line

Amelogenesis imperfecta (AI) is a genetically heterogeneous group of diseases that result in defective development of tooth enamel. Mutations in several enamel proteins and proteinases have been associated with AI. The object of this study was to evaluate evidence of etiology for the six major candidate gene loci in two Brazilian families with AI. Genomic DNA was obtained from family members an...

2014
Yan Zhang Ji-Yeon Kim Orapin Horst Yukiko Nakano Li Zhu Ralf J. Radlanski Sunita Ho Pamela K. Den Besten

Dental fluorosis is characterized by subsurface hypomineralization and increased porosity of enamel, associated with a delay in the removal of enamel matrix proteins. To investigate the effects of fluoride on ameloblasts, A/J mice were given 50 ppm sodium fluoride in drinking water for four weeks, resulting serum fluoride levels of 4.5 µM, a four-fold increase over control mice with no fluoride...

Journal: :European journal of medical genetics 2016
Mohammad Shahid Hanan A Balto Nouf Al-Hammad S Joshi Hesham Saleh Khalil Ali Mohammed Somily Nasr Abdul-Aziz Sinjilawi Sameer Al-Ghamdi Muhammad Faiyaz-Ul-Haque Varinderpal S Dhillon

Tooth agenesis in human being is the most common congenital anomaly associated with dental development. Mutations in many genes such as MSH homeobox 1 (MSX1), paired box gene 9 (PAX9), ectodysplasin A (EDA) and EDA receptor (EDAR) have been associated with familial form of this condition. However, in large majority of patients, genetic cause could not be identified. The primary aim of present s...

Journal: :Brazilian oral research 2016
Cigdem Atalayin Huseyin Tezel Taner Dagci Nefise Ulku Karabay Yavasoglu Gulperi Oktem Timur Kose

This study was designed to determine the in vivo performance of three different materials as scaffolds for dental pulp stem cells (DPSC) undergoing induced odontogenic differentiation. An odontogenic medium modified by the addition of recombinant human bone morphogenetic protein 2 was used in the experimental groups to induce differentiation. Mesenchymal stem cell medium was used in the control...

2017
Rishi Mugesh Kanna Rajasekaran Shanmuganathan Veera Ranjani Rajagopalan Senthil Natesan Raveendran Muthuraja Kenneth Man Chee Cheung Danny Chan Patrick Yu Ping Kao Anita Yee Ajoy Prasad Shetty

STUDY DESIGN A prospective genetic association study. PURPOSE The etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However, studies with a larger patient subset are lacking, and candidate genes involved in other disc degeneration phenotypes have not been evaluated. We studied the prevalence of MCs and genetic associat...

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