A primo vessel was observed in the abdominal cavity in the lung cancer mouse model, and its function as an extra metastatic path was observed. In this work, we found a primo vessel accompanying a blood vessel emanating from a tumor in the skin. We also presented simple and efficient criteria to distinguish a primo vessel from a blood or a lymph vessel and from a nerve. The criteria for using DA...

In this paper we present an extension of cure models: to incorporate a longitudinal disease progression marker. The model is motivated by studies of patients with prostate cancer undergoing radiation therapy. The patients are followed until recurrence of the prostate cancer or censoring, with the PSA marker measured intermittently. Some patients are cured by the treatment and are immune from re...

Introduction: Cancer is, in essence, a genetic disease and is the second leading cause of death globally. Fortunately, many common types of cancer are treatable if detected early and of course there are many medications and treatments available today. Among the new methods to treat cancer, radiotherapy seems to be hopeful in patients with malignancies. This work investigates th...

background: iodine brachytherapy sources with low photon energies have been widely used in treating cancerous tumors. dosimetric parameters of brachytherapy sources should be determined according to aapm tg-43u1 recommendations before clinical use. monte carlo codes are reliable tools in calculation of these parameters for brachytherapy sources. materials and methods: dosimetric parameters (dos...

In this paper, the pricing of a European call option on the underlying asset is performed by using a Monte Carlo method, one of the powerful simulation methods, where the price development of the asset is simulated and value of the claim is computed in terms of an expected value. The proposed approach, applied in Monte Carlo simulation, is based on the Black-Scholes equation which generally def...

CONTEXT Despite widespread use of serum prostate-specific antigen (PSA) testing to detect prostate cancer, the relative effectiveness of different PSA screening strategies is unknown. OBJECTIVE To compare prostate cancer mortality, PSA testing rates, and biopsy rates using various PSA screening strategies, including the standard strategy of annually testing men aged 50 through 75 years. DES...

background: monte carlo and experimental relative dose determination in a water phantom, due to a high dose rate (hdr) 192ir source is presented for real energy spectrum and monochromatic at 356 kev. materials and methods: the dose distribution has been calculated around the 192ir located in the center of 30 cm ×30 cm ×30 cm water phantom using mcnp4c code by monte carlo method. relative dose v...

introduction: clinical application of encapsulated radioactive brachytherapy sources has a major role in cancer treatment. in the present research, the effects of different tissue densities on the dose distribution of a 103pd brachytherapy source in a spherical phantom of 50 cm radius have been studied. material and methods: as is well known, absorbed dose in tissue depends to its density, but ...

OBJECTIVE To compare the diagnostic outcomes of the current approach of transrectal ultrasound (TRUS)-guided biopsy in men with suspected prostate cancer to an alternative approach using multiparametric MRI (mpMRI), followed by MRI-targeted biopsy if positive. DESIGN Clinical decision analysis was used to synthesise data from recently emerging evidence in a format that is relevant for clinica...

Background: The dosimetric parameters required in lung cancer radiation therapy are taken from a homogeneous water phantom; however, during treatment, the expected results are being affected because of its inhomogeneity. Therefore, it becomes necessary to quantify these deviations.Objective: The present study has been undertaken to find out inter- and intra- lung density variations and its dosi...