Pancreatic β cells are sensitive to oxidative stress, which is one of the predominant causes of cell damage and the emergence of diabetes. The identification of effective therapeutic strategies to protect pancreatic cells from oxidative stress has increased interest in the screening of antioxidants from natural products. The present study aimed to investigate the protective effects of morin aga...

BACKGROUND Cyclophosphamide (CPX) has many adverse effects, partly due to oxidative stress induction in various tissues. Morin is one of the natural flavonoids with strong antioxidant properties. OBJECTIVES The aim of the current research was to estimate the influence of morin on changes in antioxidant parameters in rat livers after cyclophosphamide administration. MATERIAL AND METHODS The ...

High fructose (HF) feeding induces a moderate increase in blood pressure in rats, which is associated with insulin resistance, hyperinsulinemia, and hypertriglyceridemia. In the present study, we examined the chronic effect of morin, a flavonoid isolated from medicinal plants, on blood pressure, lipid profiles, and serum insulin and glucose in HF-induced hypertensive rats. Rats were divided int...

We prove that the homotopy class of a Morin mapping f : P p → Q with p − q odd contains a cusp mapping. This affirmatively solves a strengthened version of the Chess conjecture [5],[3]. Also, in view of the Saeki-Sakuma theorem [10] on the Hopf invariant one problem and Morin mappings, this implies that a manifold P p with odd Euler characteristic does not admit Morin mappings into R for p ≥ 2k...

We aimed to investigate the effect of morin hydrate on neural stem cells (NSCs) isolated from mouse inner ear and its potential in protecting neuronal hearing loss. 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) and bromodeoxyuridine incorporation assays were employed to assess the effect of morin hydrate on the viability and proliferation of in vitro NSC culture. The N...

The potential role of morin in the treatment of diabetes along with its antihyperlipedemic effects was studied in streptozotocin-induced diabetic rats. Diabetes was induced in male Wister rats by single intraperitoneal injection (i.p) of 50 mg/kg streptozotocin. Morin was administered orally at doses of 50 and 100 mg/kg for 45 days. At the end of this experiment the effect of morin on plasma gl...

Protection of ascorbic acid (AA) (vitamin C) from Cu(II)-catalyzed autoxidation is an important aspect of antioxidant chemistry. The autoxidation of AA in the absence and presence of Cu(II) ions was investigated in aerated solution at room temperature and I = 0.1 ionic strength (KNO(3)); the effects of three different flavonoids of similar structure (quercetin, morin and catechin) and their mix...