Nitric oxide (NO), a putative intercellular messenger in the CNS, may be involved in certain forms of synaptic plasticity and learning. This article reports a series of experiments investigating the effects of N omega-nitro-L-arginine methyl ester (L-NAME) upon various forms of learning and memory in the watermaze. L-NAME (75 mg/kg, i.p., sufficient to bring about > 90% inhibition of NO synthes...

I have delayed writing this review because I have long admired the ability of Dr. Morris Fishbein to write about medicine, even though I have only rarely shared his political views. His autobiography comes as a great disappointment to me because I can find little in it of interest. I finally rose from my apathy to write this notice because a Yale medical student asked, "Who is Morris Fishbein?"...