Genetic information is stored in living organisms in DNA, RNA and protein molecules. The primary structure of these molecules is a linear chain, and hence they can be viewed as sequences of letters. This sequential biological information can be transferred between DNA, RNA and protein molecules. The so-called “central dogma of molecular biology” describes which types of transfers are allowed: i...

In this paper we describe some utilizing conditions of a recently published tool that offers two basic functions for the classical problem of discovering motifs in a set of promoter sequences. For the first it is assumed that not necessarily all of the sequences possess a common motif of given length l. In this case, CHECKPROMOTER allows an exact identification of maximal subsets of related pro...

UNLABELLED Transcription factors and the short, often degenerate DNA sequences they recognize are central regulators of gene expression, but their regulatory code is challenging to dissect experimentally. Thus, computational approaches have long been used to identify putative regulatory elements from the patterns in promoter sequences. Here we present a new algorithm "POWRS" (POsition-sensitive...