Purpose: Synkinesis results from nerve miswirings and causes aberrant movements of the affected muscles. We present a series cases rare congenital ocular synkinesis involving extraocular muscles levator palpebrae superioris speculate possibility classifying these entities in spectrum cranial dysinnervation disorder. Methods: Records patients with diagnosis were analyzed retrospectively. sex, la...

The aim of the present study is to investigate if the nucleus raphe obscurus (NRO) participate in regulating the gallbladder motility in rabbits. Rabbits were fasted for about 20-24 hours. After anesthetization with urethane, an incision was made at the middle of the abdomen and the gallbladder was exposed. A frog bladder connected with force transducer was inserted into the gallbladder through...

Chronic idiopathic intestinal pseudo-obstruction (CIIP), a syndrome of ineffectual motility due to a primary disorder of the enteric nerve or muscle, is rare and is a disorder of intestinal motility, characterized by recurrence of continuous symptoms and signs of intestinal obstruction in the absence of true mechanical obstruction. It is impossible to identify by clinical appearance and routine...

Corticotropin releasing factor (CRF) is one of the most important factors in the mechanism of stress-induced stimulation of colonic motility. However, it is controversial whether stress-induced stimulation of colonic motility is mediated via central or peripheral CRF receptors. We investigated the hypothesis that peripherally injected CRF accelerates colonic motility through the central CRF rec...

Cell migration is central to development and post-traumatic regeneration. The differential increase in 6-sulphated chondroitins during axonal growth in both crushed sciatic nerves and brain development suggests that chondroitin 6-sulphotransferase-1 (C6ST-1) is a key enzyme that mediates cell migration in the process. We have cloned the cDNA of the C6ST-1 gene (C6st1) (GenBank accession number ...

As the integrity of the omnipause neurons located in the nucleus raphe interpositus is a prerequisite of normal ocular motility, cell and neurofibrillary tangle densities were determined in 13 Steele-Richardson-Olszewski syndrome (SROS) cases [eight with supranuclear gaze palsy (SGP) and five without] and six controls. Compared with normal controls, cases with SGP were associated with approxima...

The aim of the study was to investigate the effect of electrical pelvic nerve stimulation (PNS) on recto-anal motility. The response to PNS was investigated in 8 alpha-1-chloralose anaesthetized pigs. Anal and rectal pressure and rectal cross sectional area (CSA) were recorded by manometry and impedance planimetry, respectively. A new probe design allows measurements of CSA at 5 different locat...

UNLABELLED The disease mechanisms associated with onset and secondary effects of rotavirus (RV) diarrhea remain to be determined and may not be identical. In this study, we investigated whether onset of RV diarrhea is associated with increased intestinal permeability and/or motility. To study the transit time, fluorescent fluorescein isothiocyanate (FITC)-dextran was given to RV-infected adult ...

Sympathetic ganglia from newborn rats and guinea-pigs were grown in modified Rose chambers and examined with scanning electron microscopy after 5-7 days. The cell types seen were macrophages, neurons, glial cells and connective tissue cells. They presented a wide range of surface morphologies and 3-dimensional configurations, from spheroid with an irregular surface to flattened with a smooth su...

Achalasia is a primary esophageal motility disorder that involves failure of the lower sphincter to relax in response swallowing. Specifically, becomes hypertensive, and there an absence peristalsis esophagus. The pathophysiology thought be due loss inhibitory nerve function from autoimmune attack targets myenteric nerves. As result, these abnormalities lead functional obstruction at gastroesop...