Malignant melanoma of the oral cavity is a rare neoplasm and it is only 0.5% of the malignant neoplasms of the oral cavity, and less than 10% of all the malignant melanomas. The mean age for patients with oral melanoma is from 40 to 70 years; with a higher frequency between the 50 and 60 years. Pigmentation areas are frequently noted before diagnosis of this neoplasm. Some predisposing factors ...

objectives this study investigates the prevalence of burning mouth symptom for the first time in an institutional group of patients in shiraz, iran, among whom some were found to have bms through excluding the recognizable physical or biochemical causes of mouth burning. methods in this cross sectional study, from the existing records of 2 533 patients who referred to shiraz dental school since...

HIV-positive as well as other immunocompromised women and men have increased risk of human papillomavirus (HPV)-associated nogenital and oral cancers. The effectiveness of a HPV vaccine to reduce the incidence of these tumors in immunocompromised individuals ay depend on several factors, including the effects of immunocompromise on the response to vaccination, the extent of prior infection ith ...

IN 1950 Ledlie and Harmer published a report on 800 patients with cancer of the mouth seen at the Royal Marsden Hospital (then the Royal Cancer Hospital) between January, 1936, and December, 1945, with a minimum follow-up period of 3 years. These same patients have been reviewed again up to the end of December, 1956, the minimum follow-up period being 11 years. The success or failure of the fir...

The most common malignancy to involve the oral cavity and oropharynx is squamous cell carcinoma (SCC). Because these oral cancers share an origin from the squamous epithelium, the pathology of oral SCC might be expected to be uniform and its diagnosis repetitive. In reality, the morphologic diversity in SCC, along with the propensity for reactive processes of the oral cavity to mimic SCC histol...

UNLABELLED Cervical metastasis represent the most relevant prognostic factor in carcinomas of the mouth. Clinical and histological factors are associated with the development of cervical metastasis; however, research on molecular factors has been broadly carried out in recent years. AIM The aim of this study is to analyze the association of the Cyclin D1 as a risk factor for the presence of c...

In this issue of Clinical Cancer Research , Poh et al. (1) show the effectiveness of a simple handheld light (blue excitation light at 400-460 nm) to clarify the true extent of tumor spread and, in turn, guide complete removal of oral cancers in the operating room. Optical changes (specifically, loss of fluorescence) in the epithelium in and around oral cancers was used to map the ‘‘field of ca...

a tumor in the mouth with a central ulcer, located on the hard and soft palate, measuring approximately 6cm (Figure 1A). A panoramic radiograph showed bone lysis in teeth 25 to 28, maxillary sinus involvement and extension into the floor of the orbit. (Figure 1B). A biopsy was made and the specimen was sent to the Pathology Unit. Histopathology revealed a malignant gland epithelial neoplasm cha...

Adenoid cystic carcinoma (ACC) is a rare neoplasm that usually arises from minor salivary glands. It is characteristically locally infiltrative, exhibiting perineural invasion, has a tendency for local recurrence and prolonged clinical course. A 60 year old male, chronic smoker presented with swelling of the left cervical lymph node since two months. Examination revealed a solitary firm, non te...