The amount of video content and the number applications based on multimedia information increase each day. development new coding standards is a challenge to compression rate other important features with reasonable in computational load. Joint Video Experts Team ITU-T Coding Group ISO/IEC Moving Picture (MPEG) have worked together develop versatile standard, finalized July 2020 as Internationa...

This White Paper promotes the concept and the idea behind MPEG-A in general and Multimedia Application Formats (MAFs) in particular. To this end, the White Paper is published via the MPEG Web site. The document is targeted at people in MPEG who are not familiar with MPEG-A yet as well as at industry representatives who may not be involved with the MPEG standardization process. 1. The MPEG-A Sta...

The ISO MPEG committee, after successful completion of the MPEG-1 and the MPEG-2 standards is currently working on MPEG-4, the third MPEG standard. Originally, MPEG-4 was conceived to be a standard for coding of limited complexity audio-visual scenes at very low bit-rates; however, in July 1994, its scope was expanded to include coding of scenes as a collection of individual audio-visual object...

HM-3, designed by our laboratory, is a polypeptide composed of 18 amino acids. Pharmacodynamic studies in vivo and in vitro indicated that HM-3 could inhibit endothelial cell migration and angiogenesis, thereby inhibiting tumor growth. However, the half-life of HM-3 is short. In this study, we modified HM-3 with different polyethylene glycols (PEG) in order to reduce the plasma clearance rate, ...

A new class of methoxy-poly(ethylene glycol) (mPEG) derivatives having a cleavable group of oligo-lactic acid (OLA) was synthesized by ring opening polymerization of L-lactide using a terminal hydroxyl end of mPEG as an initiator. The synthesized mPEG derivatives had 0.8 and 3.6 lactic acid units based on the MALDI-TOF data. A terminal end group of mPEG-OLA was further activated with p-nitrophe...