BACKGROUND Mucociliary clearance is impaired in patients with Young's syndrome (obstructive azoospermia with recurrent sinobronchial disease), cystic fibrosis, and primary ciliary dyskinesia. No defect of cilia or mucus has been detected in Young's syndrome. METHODS Ciliary function and ultrastructure, including ciliary orientation, were studied quantitatively in 20 patients with Young's synd...

more illustrations have been added. The main changes in the text are in the descriptions of the ciliary muscle, the substantia propria of the cornea, the vitreous, the zonule of Zinn, the distribution of the lachrymal fluid, the muco-cutaneous junction at the lid margin, the precorneal film, the retinal capillaries and the central connections of the visual apparatus. This is a superb book from ...

<p>Epistaxis is a health ENT problem which still current, this one of the commonly encountered emergencies in Rhinology. The nasal mucosa suffered influence systemic, local, metabolic or hormonal disorders causing slowdown muco-ciliary function during pregnancy. These observations relate clinical and therapeutic particularities management for severe epistaxis women last trimester woman's ...

Primary ciliary dyskinesia (PCD) is a chronic, inherited disease characterized by ciliary dysfunction leading to defects in mucociliary clearance, thus causing upper and lower respiratory problems such as sinusitis and bronchiectasis as well as infertility. Diagnostic workup includes a combination of different techniques such as nasal nitric oxide measurement, high-speed video microscopy analys...

Primary ciliary dyskinesia is a genetically inherited syndrome characterized by cilia immotility or dysmotility. Deficiency in mucociliary clearance produces chronic respiratory infections since birth, male sterility by spermatozoid immotility and situs inversus in 40-50% of patients (Kartagener's syndrome). Diagnosis is made by analyzing cilia motility with high-speed digital video and ciliar ...

Airway mucociliary clearance is a first-line defense of the lung against inhaled particles and debris. Among individuals with alcohol use disorders, there is an increase in lung diseases. We previously identified that prolonged alcohol exposure impairs mucociliary clearance, known as alcohol-induced ciliary dysfunction (AICD). Cilia-localized enzymes, known as the ciliary metabolon, are key to ...

The brooding bivalves, Nutricola tantilla and N. confusa overlap in their geographic distributions, habitats, and modes and timing of reproduction. Based on previous studies we infer that males of both species release spermatozoa into the water column; while females retain developing embryos in a brood chamber. Females release fully formed juveniles and there is no pelagic larval stage. We hypo...

BACKGROUND Our prior work on congenital heart disease (CHD) with heterotaxy, a birth defect involving randomized left-right patterning, has shown an association of a high prevalence of airway ciliary dysfunction (CD; 18/43 or 42%) with increased respiratory symptoms. Furthermore, heterotaxy patients with ciliary dysfunction were shown to have more postsurgical pulmonary morbidities. These findi...

The airway is covered by multicilia that beat in a metachronous manner toward the mouth to eliminate debris and infectious particles. Coordinated one-directional beating is an essential feature of multicilia in the airway to guarantee proper mucociliary clearance. Defects in ciliary motility lead to primary ciliary dyskinesia (PCD), with major symptoms including bronchitis and other chronic res...