نتایج جستجو برای: mucoadhesive film
تعداد نتایج: 92192 فیلتر نتایج به سال:
Polymers are tools used in novel drug delivery system to modify the drug release of pharmaceutical dosage form. Polyox is hydrophilic polymer made of non-ionic homopolymer of ethylene oxide. Polyox is popular for its film forming, binding, lubricating, mucoadhesive, viscosity imparting property in pharmaceuticals. Polyox are available in various grades based on its molecular weight. Lower molec...
Objective: The Losartan potassium mucoadhesive buccal tablet were prepared using mucoadhesive polymers such as Carbopol 940P, pectin, sodium CMC, Sodium alginate, HPMC K4M, HPMC K15M and HPMC K100M in alone and in combination as release retarding agent to prolong the drug release and to avoid first pass metabolism. Methods: The mucoadhesive buccal tablets were prepared by direct compression met...
To develop a new mucoadhesive film containing an analgesic combining clinical efficacy and patient comfort, we prepared and evaluated a two-layered film consisting of an adhesive layer containing indomethacin (IM) as the active ingredient and carboxyvinyl polymer (CP) as a bonding agent and a nonadhesive layer containing polyethylene glycol (PEG) to improve film texture. In in vitro and in vivo...
The main aim of the present investigation was to develop in situ gelling mucoadhesive liquid suppositories of ondansetron by using mucoadhesive polymers such as sodium alginate, methyl cellulose and polyvinylpyrrolidone. Polyethylene glycol was used to modify gelation temperature. Mucoadhesive liquid suppositories of ondansetron were prepared by adding mucoadhesive polymers (0.8% w/w) to the fo...
The purpose of current article focuses on polymers used in mucoadhesive drug delivery system. The term “mucoadhesive” is defined as the “attachment of drug elongated with asuitable carrier like natural or synthetic polymer to mucus and/or an epithelial surface”. It is a popular novel drug delivery system because relatively permeable of mucous membranes, and mucus have higher blood flow therefor...
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