We report a rare case of prostatic carcinoma associated with cystic degeneration. Cystic masses within the prostate are known. Benign cystic masses are more common and include congenital cysts of mullerian duct or mesonephric duct origin. Acquired cysts can be either retention cysts, parasitic or malignant in nature. Cysts accompanying prostatic carcinoma are moreover rare. The acute retention ...

We report a case of congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency in a Chinese genotypic male patient. Despite the male genotype, normal female external genitalia were present and with the introduction of cyclical oestrogen therapy withdrawal bleeding occurred, confirming the presence of functional endometrial tissue. We believe this to be the first report of persistent ...

Mutations were introduced into conserved steroidogenic factor 1 (SF1)- and SOX9-binding sites within the endogenous mouse Mullerian inhibiting substance (Mis) promoter. Male mice homozygous for the mutant SF1-binding site correctly initiated Mis transcription in fetal testes, although at significantly reduced levels. Surprisingly, sufficient MIS was produced to eliminate the MUllerian ducts. In...

Ten laboratories in an external quality assurance scheme used the same assay to measure anti-müllerian hormone concentration (Beckman Coulter Gen II) and received twenty serum samples distributed over a 15 month period. The mean bias for all results was only -0.089%, but there was large coefficient of repeatability of 38.8% (sample bias ranged from -37.9% to +54.7%). While each laboratory showe...

Persistent Mullerian Duct Syndrome (PMDS) associated with transverse testicular ectopia (TTE) is rare. Ten cases have been reported in the past. Accurate diagnosis with karyotype and histological analysis is crucial. Surgical management should be geared toward preservation of fertility when possible.

INTRODUCTION Persistent Mullerian duct syndrome (PMDS) is a rare type of male pseudohermaphroditism. Transverse testicular ectopia (TTE) is characterized by one testis moving to the opposite side and both testes traversing the same inguinal canal. CASE PRESENTATION An 11-month-old boy presented with bilateral cryptorchidism. The left testis was not palpable; the right testis was canalicular w...

OBJECTIVE To determine age-specific serum anti-Müllerian hormone (AMH) values for women presenting to U.S. fertility clinics. DESIGN Retrospective study. SETTING Single clinical reference laboratory. PATIENT(S) A total of 17,120 women of reproductive age ranging from 24 to 50 years old. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Determination of single-year median and mean AMH valu...

ullerian duct anomalies (MDAs) are relatively common disorders that are particularly responsible for obstetrical complications and have a prevalence of about 3%−4% in the general population (1, 2). Uterine malformations may result from arrested development of the mullerian ducts, failure of fusion of the mullerian ducts or failure of resorption of the median septum (1, 2). Several classificatio...