Currently, a pharmacological disease-modifying treatment for dementia is not available, but different non-pharmacological approaches appear to be useful. In this chapter, we describe traditional treatments such as cognitive and emotion-oriented interventions, sensory and multi-sensory stimulation interventions and also potential‐ ly alternative interesting options such as behavioural therapy, a...

Abstract Objective: To evaluate and compare the analgesic effects of caudal epidural administration of lidocaine (LIDO), caudal laser radiation and epidural lidocaine plus laser radiation in horses. Study design: A blinded, randomized, prospective, experimental cross-over study. Animals: Five healthy horses, 15.7 +/- 4.9 years of age, weighing 240 +/- 37 kg. Methods: The...

BACKGROUND Sensory stimulation of the forelimb extremities constitutes a well-established experimental model that has consistently shown to activate dopamine (DA) neurotransmission in the mammals' forebrain. OBJECTIVES To visualize in vivo this modification of striatal DA release in healthy human volunteers using Positron Emission Tomography (PET) and [(11)C]raclopride. Experiments in humans ...

The effects of anesthetics on the transmission and processing of sensory information within the thalamocortical pathway and the underlying mechanism are not fully understood. Using the extracellular recording technique, we investigated the changes of spontaneous and stimulation-evoked activities within and between the ventral posteromedial nucleus (VPM) and primary somatosensory cortex barrel f...

Digitalization of human taste has been on the back burners multi-sensory media until beginning decade, with audio, video, and haptic input/output(I/O) taking over as major sensory mechanisms. This article reviews consolidated literature augmented reality (AR) in modulation stimulation sensation humans using low-amplitude electrical signals. Describing multiple factors that combine to produce a ...

Background: Anesthesia duration can play a significant role in post-operative complications. Therefore, the present study investigated the effect of auditory sensory stimulation with a familiar voice on anesthesia return in patients undergoing rhinoplasty. Methods: This study was performed on 80 patients who were candidates for rhinoplasty surgery in Yazd Trauma and Burn Hospital from Septembe...

UNLABELLED Why are some people strongly motivated by intense sensory experiences? Here we investigated how people encode the value of an intense sensory experience compared with economic reward, and how this varies according to stimulation-seeking preference. Specifically, we used a novel behavioral task in combination with computational modeling to derive the value individuals assigned to the ...