Given the heterogeneity of autism spectrum disorder, an important limitation of much autism spectrum disorder research is that outcome measures are statistically modeled as separate dependent variables. Often, their multivariate structure is either ignored or treated as a nuisance. This study aims to lift this limitation by applying network analysis to explicate the multivariate pattern of risk...

mitochondrial disorders (mids) may occasionaly go along with dysmorphism but hand deformities, as in the following case, have been only rarely reported. a 72 year old female with ptosis, hypoacusis, tremor, myopathy, diabetes mellitus, arterial hypertension, severe cardiac disease, pulmonary hypertension, gastric carcinoid, hepatopathy, generalised atherosclerosis, anemia, polyarthrosis, and hy...

In the last ten years, several risk factors that increase the risk of venous thrombosis have been discovered. Venous thrombosis is a multicausal disease in which several risk factors, both genetic and acquired, have to occur simultaneously to cause thrombosis. This means that most individuals with single thrombophilia are asymptomatic. Although testing thrombosis patients and their relatives fo...

severe acute respiratory syndrome (sars) is a fetal communicable respiratory disease, known as atypical pneumonia. this disease first appeared in china on november 2002 and spread very fast in various parts of the world especially in asia. number of reported cases of sars from november 2002 to may 2003 were about 8046 of which 6825 patients died. sars is caused by coronavirus, and symptoms of d...

Mental disorders are among the leading causes of global disease burden. To respond effectively, a strong understanding structure psychopathology is critical. We empirically compared two competing frameworks, dynamic-mutualism theory and common-cause theory, that vie to explain development psychopathology. formalized these theories in statistical models applied them change general factor (p fact...

Introduction and purpose Microscopic colitis is multicausal inflammatory bowel disease, which affects mostly elderly, particularly women. It a cause of chronic, watery diarrhea. MC usually presents macroscopically normal, thus diagnosis requires colonoscopy histological examination colonic biopsies. doesn’t increase risk colon cancer. However, it leads to impaired patients’ quality life reduced...

upper respiratory tract diseases (urtd) are common clinical problem in cats worldwide. feline calicivirus (fcv) and feline herpesvirus type 1 (fhv-1) are the main primary pathogens. feline immunodeficiency virus (fiv) and feline leukemia virus (felv) are also among the most common infectious diseases of cats which suppress the immunity. oropharyngeal and conjunctival swabs and blood samples wer...

background: application noninvasive ventilation in the patients with exacerbation of chronic obstructive pulmonary disease (copd) reduced mortality. this case-control study was designed to compare efficiency and outcome of non-invasive (niv) versus invasive positive pressure ventilation (ippv) in respiratory failure due to copd methods: the patients were assigned to niv or ippv intermittantly.t...

Abstract One of the main cause of severe respiratory infection in infants and young children is respiratory syncytial virus (RSV). The disease can also occur in adults and elderly individuals and clinically not to be differentiated from other viral respiratory infection. The disease causes bronchiolitis, and sometimes pneumonia in new born and young children which requires hospital care. To di...