OBJECTIVES Acro-osteolysis (bony resorption of the terminal digital tufts) is a well-recognized, but under-researched, manifestation of SSc. Our aim was to investigate the hypothesis that acro-osteolysis is associated with (i) the severity of digital ischaemia and (ii) the presence of calcinosis. METHODS This was a retrospective study of 101 patients with SSc in whom hand radiographs taken be...

conclusions gorham’s disease has several manifestations as primary bone involvement. as in this rare case the ulna may be affected first and then the disease may spread to adjacent bones. more studies are needed to better recognize the behavior of this rare disease. introduction gorham’s disease is a rare musculoskeletal disease which causes progressive osteolysis and is characterized by massiv...

liposarcoma is a common malignant soft tissue tumor, accounting for 10% to 16% of all sarcomas. multicentric myxoid liposarcoma is an uncommon condition. differentiation between several primary tumors and metastasis of a single liposarcoma represents the main difficulty in diagnosis. a 47-years old woman presented with right thigh myxoid liposarcoma and underwent wide margin tumor resection. ot...

Four cases of severe osteolysis of bones subsequent to camel bite are described. The first had osteolysis of the ribs with traumatic diaphragmatic hernia. Two cases had similar appearances of gross osteolysis of the shafts of the radius and ulna, whilst one had osteolysis of the humeral shaft. The similarities in the radiological appearances especially of the gross osteolysis at the site of tra...

multicentric reticulohistiocytosis (mrh) is a rare proliferative histiocytic disease of ‎unknown cause with potentially disabling nature. primary manifestations are involvement ‎of skin and joints. the articular destruction can lead to permanent joint deformities. our ‎patient was a 47 year-old woman with bilateral symmetrical polyarthritis and reddish- ‎brown papulonodular cutaneous lesions. t...

BACKGROUND Multicentric Castleman's disease describes a group of poorly understood lymphoproliferative disorders driven by proinflammatory hypercytokinaemia. Patients have heterogeneous clinical features, characteristic lymph node histopathology, and often deadly multiple organ dysfunction. Human herpesvirus 8 (HHV8) causes multicentric Castleman's disease in immunosuppressed patients. The caus...

AIMS One of the reason for Latarjet procedure failure may be coracoid graft osteolysis. In this study, we aimed to understand if a better compression between the coracoid process and the glenoid, using a mini-plate fixation during the Latarjet procedure, could reduce the amount of coracoid graft osteolysis. MATERIALS AND METHODS A computed tomography scan analysis of 26 prospectively followed...

Acro-osteolysis is a bone resorption reaction that progresses slowly in the distal phalanx of hand and foot associated with various diseases. It can be classified as idiopathic or secondary. Although mechanism acro-osteolysis has not been fully elucidated, presence chronic ischemic injury appears to have significant effect, metabolism dysregulation due accompanying calcinosis peripheral neuropa...

The Gorham-Stout Syndrome (Gorham's massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report six cases of the condition and present evidence that osteolysis is due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy such as with calcitonin or bisphosphon...