Effective analgesia and blockade of the perioperative stress response may improve outcome and accelerate recovery following thoracic surgery. Although different approaches can achieve the same goal, it seems that a multimodal pain management based on the use of synergistic drugs provides better analgesia. The route of administration of the postoperative analgesic drugs is important, and epidura...

Background. Elderly patients have unique age-related comorbidities that may lead to an increase in postoperative complications involving neurological, pulmonary, cardiac, and endocrine systems. There has been an increase in the number of elderly patients undergoing surgery as this portion of the population is increasing in numbers. Despite advances in perioperative anesthesia and analgesia alon...

BACKGROUND AND OBJECTIVE Adequate analgesia after sternotomy reduces postoperative adverse events. There are various methods of treating pain after heart surgery, such as infiltration with a local anesthetic, nerve block, opioids, non-steroidal anti-inflammatory drugs, alpha-adrenergic agents, intrathecal and epidural techniques, and multimodal analgesia. CONTENT A review of the epidemiology,...

The prevalences of complex regional pain syndrome, phantom limb pain, chronic donor-site pain, and persistent pain following total joint arthroplasty are alarmingly high. Central nervous system plasticity that occurs in response to tissue injury may contribute to the development of persistent postoperative pain. Many researchers have focused on methods to prevent central neuroplastic changes fr...

Aggressive and complete surgical excision is the treatment of choice for fibrosarcomas in cats. Thorough preoperative planning and meticulous surgical technique are necessary for optimal cosmetic, functional, and oncologic outcome. Perioperative pain management with an emphasis on preemptive analgesia and multimodal analgesia is essential to minimize patient morbidity.

Background and aim "Fast-Track Surgery" is an interdisciplinary multimodal perioperative treatment that includes intra-operative anesthesia and post-operative analgesia using drugs and ways of administration as thoracic epidural analgesia and lidocaine infiltration of the incisions for post-operative pain relief, in combination with the immediate mobilization of the patient, the early oral nutr...

Introduction: This study looked at how pharmacology affected surgical anatomy and patient outcomes. Methods: The research included a total of 162 participants who were having elective surgery. Propofol or sevoflurane was randomly allocated to patients for the initiation maintenance anesthesia. Acetaminophen, nonsteroidal anti-inflammatory medications (NSAIDs), opioids used in combination allevi...