none of the approved immunomodulatory drugs in adults multiple sclerosis (ms) patients have been officially approved for the pediatric patients and are currently used off-label in this population. in this study, we evaluated the effectiveness and tolerability of intramuscular interferon beta1-a (avonex®) and subcutaneously injected interferon beta1-b (betaferon®) in children with definite relap...

a 54 year old man with history of cardiomyopathy and chronic fibrillation first presented with bloody diarrhea. then during the assessment of his abnormal lab. data revealed cast nephropathy in renal biopsy, gamma peak in protein electrophoresis and fine lytic lesions in skull graphy. his bone marrow aspiration showed multiple myeloma and blood smear revealed plasma cell leukemia. our patient w...

in this paper, the cost and income efficiency models have been considered with regard to the multiple objective programming structures. for finding the efficient points in purposed molp problem, some various methods like lexicography & the weighted sum can be used. so by introducing the molp problem the cost & income efficiencies will be achieved. in the present study, the molp problem ...

conclusions orem’s self-care model is significantly effective in reducing the fatigue of multiple sclerosis patients. objectives to determining the effect of orem’s self-care model on fatigue in multiple sclerosis patients. patients and methods this research involved a clinical trial. sixty-three multiple sclerosis patients at the vice-chancellor in treatment affairs of yasuj university of medi...

introduction plasma cell dyscrasias are characterized by a monoclonal neoplastic proliferation of plasma cells. solitary bone plasmacytoma (sbp) is a local form of the disease with the vertebrae and long bones being the most frequently encountered sites. its prevalence in the maxillofacial area is extremely rare. case presentation a 70-year-old caucasian male patient was referred for the extrac...

normal 0 false false false en-us x-none ar-sa background: to evaluate seizure characteristic among multiple sclerosis patients with coexistent seizure activity compared to control group. materials and methods: this study is a cross-sectional study which was conducted by reviewing the clinical records of patients with definite diagnosis of ms according to mcdonald’s criteria from march 2007 to j...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) which causes demyelination of the nerve fibers. the etiology of this disease is not well understood but it is believed that t helpers play a central role in ms. numerous findings support the view that th17 cells play an essential role in pathogenesis of ms and il-17 secreting t (th17) cells have a role in infla...

introduction: multiple myeloma represents a malignant proliferation of plasma cells derived from a single clone and it results in bone pain or fracture, renal failure, susceptibility to infections, anemia, and hypercalcemia. the hyperviscosity syndrome is rare. cryoglobulins are immunoglubulins that precipitate in the cold temperature less than 37˚c. monoclonal cryoglobulins are associated with...