Background. Spasticity is prevalent and disabling in persons with multiple sclerosis (MS), and the development of the Multiple Sclerosis Spasticity Scale-88 (MSSS-88) provides an opportunity for examining the perceived impact of spasticity and its association with gait in this population. Purpose. This study examined the association between the perceived impact of spasticity and spatio-temporal...

OBJECTIVE Multiple Sclerosis Spasticity Scale (MSSS)-88 has been developed for self-assessment of spasticity symptoms in patients with multiple sclerosis (MS). The objective of this study was to validate MSSS-88 and evaluate the psychometric properties in patients with MS in Serbia. METHODS The study comprised 65 MS patients with spasticity. MSSS-88 consists of 88 items grouped in eight secti...

introduction: more than 50 scoring systems have been published for classification of trauma patients in the field, emergency room, and intensive care settings, so far. the present study aimed to compare the ability of trauma injury severity score (triss) and acute physiology and chronic health evaluation (apache) iii in predicting mortality of intensive care unit (icu) admitted trauma patients....

INTRODUCTION Tau protein is a potential marker of neuronal damage. The aim of the study is to investigate its potential role as a marker of brain atrophy in multiple sclerosis (MS). MATERIALS AND METHODS Cerebrospinal fluid (CSF) and blood samples were collected from 48 patients with multiple sclerosis. Total-tau (t-tau) and phospho(181Thr)-tau (p-tau) concentrations were assayed with commerc...

Objective To characterize T-cell receptors (TCRs) and identify target epitopes in multiple sclerosis (MS). Methods Peripheral blood mononuclear cells were obtained from 39 MS patients 19 healthy controls (HCs). TCR repertoires for α/β/δ/γ chains, diversity, V/J usage determined by next-generation sequencing. β chain compared with affectation status using a novel clustering method, Grouping of L...

introduction: multiple sclerosis (ms) is one of the most common disabling diseases in young adults. common manifestations include fatigue, bladder and bowel disorders, pain, mobility problems, and cognitive impairment. these symptoms seriously affect the activity of daily living (adl) of people with ms. the purpose of this study to investigate relationship between disability severity and adl in...

Introduction: Metabolic Syndrome Severity Score (MSSS) is a new clinical prediction rule (CPR) for diagnostic and therapeutic decisions and employs available components (sex, age, race, systolic blood pressure, waistline circumference, high-density lipoprotein, triglycerides and fasting blood glucose). The aim of our work was to perform cross-sectional pilot trial on middle-aged healthy volunte...

background: multiple sclerosis is a common and chronic neurologic disorder. this disorder imposes physical, economic, and psychosocial burden on individuals, their families and society. this study aims to analyze the costs of multiple sclerosis disease based on the severity of disability. methods: we performed a cross‑sectional cost of illness study. this study was conducted in 332 patients of ...

BACKGROUND Fatigue is a common symptom in patients with multiple sclerosis (MS). It has significant negative effects on the quality of life of patients with the condition. There are few therapeutic modalities for fatigue, which are also usually not sufficiently effective. The aim of this study was to evaluate the efficacy of acupuncture on this common symptom of patients with MS. METHODS In t...