BACKGROUND Mumps virus infection is a potentially serious viral infection of childhood and early adulthood. In China, live attenuated S(79) mumps vaccine has been licensed for pediatric use since 1990. The objective of this study was to determine the effectiveness of live attenuated S(79) mumps vaccine against clinical mumps in outbreaks. METHODS Cases were selected from mumps outbreaks in sc...

Prior to the adoption of widespread vaccination programs, mumps virus was the leading cause of virus-induced central nervous system (CNS) disease. Mumps virus-associated CNS complications in vaccinees continue to be reported; outside the United States, some of these complications have been attributed to vaccination with insufficiently attenuated neurovirulent vaccine strains. The development of...

Introduction: The classic “Mumps” is known as a viral parotitis caused by mumps virus belonging to the genus Rubulavirus in the Paramyxoviridae family. Case Presentation: We reviewed three patients diagnosed with aseptic meningitis due to acute non-mumps associated parotitis based on clinical and laboratory findings. While there are many similarities between the clinical characteristics of clas...

PURPOSE Mumps meningitis is a common complication of mumps infection; however, information on mumps meningitis in the postvaccine era is limited. The purpose of the present study was to determine factors associated with mumps meningitis and to discuss the effect of vaccination on this disease. METHODS We retrospectively reviewed patients younger than 19 years with mumps, diagnosed at a univer...

Introduction of MMR vaccine was believed to have resulted in a decline in the incidence of measles, mumps and rubella infections. However, recent reports suggest the re-emergence of mumps infection worldwide in the vaccinated populations. It was proposed that the reason for this re-emergence was poor efficacy of MMR vaccine. The present study was aimed to investigate mumps infection in MMR vacc...

This document describes the Fortran 90 and C user interfaces to MUMPS 4.10.0 We describe in detail the data structures, parameters, calling sequences, and error diagnostics. Basic example programs using MUMPS are also provided. ∗Information on how to obtain updated copies of MUMPS can be obtained from the Web pages http://mumps.enseeiht.fr/ and http://graal.ens-lyon.fr/MUMPS/

The association of mumps with peripheral facial paralysis has been suggested, but its pathogenesis remains unclear. An 8-year-old girl simultaneously developed left peripheral facial paralysis, ipsilateral cervical herpes zoster, and bilateral mumps sialadenitis. Elevated anti-mumps and anti-varicella zoster virus IgM antibodies in serological testing indicated recent infection of mumps and rea...

In October 1988, routine immunisation against mumps was introduced in the United Kingdom as a combined measles, mumps, and rubella (MMR) vaccine for children aged 12-15 months. Although the incidence of mumps declined quickly, mathematical modelling supported the introduction of a second dose of MMR in 1996. In 1999, numbers of cases of mumps in teenagers in England and Wales began to rise. We ...

Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan. These clinical studies demonstrated that mumps virus could be a promising cancer therapeutic agent that showed significant antitumor activity against various types of cance...

The incidence of mumps infection in the UK was reduced greatly by vaccination as a component of MMR vaccine, but cases and outbreaks continue to occur. Although in specialised laboratories RT-PCR is available for detection of mumps virus RNA in clinical samples, in routine laboratories virus isolation remains a standard method for diagnosing mumps virus infection. Furthermore, isolation of mump...