BONES & JOINTS CONGENITAL DISEASES OF BONE Osteogenesis Imperfecta (OI) (Brittle bone diseases) is a group of hereditary disorders caused by gene mutations that eventuate in defective synthesis of and thus premature degradation of type I collagen. The fundamental abnormality in all forms of OI is too little bone, resulting in extreme susceptibility to fractures. The bones show marked cortical t...

The extent of ageing in the musculoskeletal system during the life course affects the quality and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed intervertebral discs are primary features of an ageing skeleton, and together they contribute to pain and loss of mobility. This review covers the cellular constituents that make up some key components of the muscu...

Tuberculosis remains a major source of morbidity and mortality worldwide, and orthopaedic surgeons working in developing nations, especially in South East Asia, are likely to encounter patients with osteoarticular manifestations of the disease. Chemotherapy is effective, and surgery serves as an adjunct for specific indications. Tuberculous osteomyelitis is the least common presentation, and th...

Geriatric and rheumatological linkages: public health implications Editors in medical journals worldwide have selected aging as the 1997 Global Theme Issue. In proposing this article, the editors of the Annals have considered the importance and implications of the growth of the very elderly population in developed countries and the widespread prevalence of musculoskeletal conditions in this age...

OBJECTIVES The aim of the present study was to identify prevalence of musculoskeletal system diseases and related factors among mothers of children with cerebral palsy. METHODS Eighty-five mothers of children with cerebral palsy were included as the treatment group, and 42 mothers of healthy children were included as the control group. Sociodemographic characteristics of all subjects were rec...

OBJECTIVE Worldwide, the use of sonography for the evaluation of the musculoskeletal system has been growing. However, radiologists in North America have been relatively slow to incorporate musculoskeletal sonography into their practices. The purpose of this article is to show the advantages of musculoskeletal sonography. CONCLUSION Musculoskeletal sonography is an important complementary too...

Various forms of intensive sport place stress on the musculoskeletal system of the horse, during both racing and training. The musculoskeletal system of the horse has an inherent ability to adapt to the demands of high speed exercise, but exceeding the threshold of adaptive capacity may result in some form of damage. Continuing racing or training may delay the repair process and put the horse a...