نتایج جستجو برای: myeloid derived suppressor cells

تعداد نتایج: 1797714  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Melissa G Lechner Alan L Epstein

In this issue of Clinical Cancer Research, Zoglmeier and colleagues show that CpG, via the induction of IFN-α, matures myeloid-derived suppressor cells to abrogate immune suppression in 2 murine solid tumor models.

Journal: :Advanced Healthcare Materials 2023

Nanoenzymes In article 2300191 by Wenli Diao, Hui Wei, Hongqian Guo, and co-workers, a Zr-CeO nanozyme is developed to possess enhanced activities mimicking superoxide dismutase catalase. Via scavenging intracellular reactive oxygen species, exerts remarkable effects on diminishing myeloid-derived suppressor cells M2-TAM immunosuppression simultaneously, eventually boosts anti-tumor immune resp...

2013
Daniela Teixeira Joaquim Soares de Almeida Bruna Visniauskas Guiomar Nascimento Gomes Aparecida Emiko Hirata Valquiria Bueno

OBJECTIVES Myeloid-derived suppressor cells contribute to the immunosuppressive microenvironment during tumor development and limit the efficacy of cancer immunotherapy. Identifying myeloid-derived suppressor cells and associated factors is the first step in creating strategies to reverse the suppressive effects of these cells on the immune system. METHODS To induce lung cancer, we administer...

The incidence of obesity, as a major health problem, has increased significantly over the past decades. This condition is associated with an increased risk of cancers, type 2 diabetes, and cardiovascular diseases. The current study aimed to investigate the effects of inflammation and changes of adipose tissue-resident immune cells on increasing the risk of cancer in obese individuals. In obesit...

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