نتایج جستجو برای: myocyte enhancer factor 2
تعداد نتایج: 3167311 فیلتر نتایج به سال:
Regulation of the process of neuronal death plays a central role both during development of the CNS and in adult brain. The transcription factor myocyte enhancer factor 2 (MEF2) plays a critical role in neuronal survival. Cyclin-dependent kinase 5 (Cdk5) mediates neurotoxic effects by phosphorylating and inhibiting MEF2. How Cdk5-dependent phosphorylation reduces MEF2 transactivation activity r...
Myocyte enhancer factor-2-activating motif and SAP domain-containing transcriptional regulator (MAMSTR) regulates its downstream through binding in promoter regions. However, molecular mechanism, particularly the DNA-binding sites, coregulatory genes are quite unexplored. Therefore, to identify genome-wide sites of MAMSTR transcription factors their genes, chromatin immunoprecipitation sequenci...
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