OBJECTIVE To systematically assess adherence of randomised trials in surgery to Consolidated Standards of Reporting Trials (CONSORT) guidelines for non-pharmacological treatments (NPT). Surgical trials are considered more difficult to design and execute than pharmacological trials. Furthermore, the original CONSORT statement does not address some aspects that are vital to the transparent report...

A multi-dimensional extra-large pore silicogermanate zeolite, named ITQ-54, has been synthesised by in situ decomposition of the N,N-dicyclohexylisoindolinium cation into the N-cyclohexylisoindolinium cation. Its structure was solved by 3D rotation electron diffraction (RED) from crystals of ca. 1 μm in size. The structure of ITQ-54 contains straight intersecting 20 × 14 × 12-ring channels alon...

Aspergillus fumigatus is an important cause of life-threatening invasive fungal disease in patients with compromised immune systems. Resistance to itraconazole in A. fumigatus is closely linked to amino acid substitutions in Cyp51A that replace Gly54. In an effort to develop a new class of molecular diagnostic assay that can rapidly assess drug resistance, a multiplexed assay was established. T...

Let $G$ be a simple graph with $n$ vertices and $\pm 1$-weights on edges. Suppose that for every edge $e$ the sum of edges adjacent to (including itself) is positive. Then weights over at least $-\frac{n^2}{25}$. Also we provide an example weighted described properties $-(1+o(1))\frac{n^2}{8(1 + \sqrt{2})^2}$.
 The previous best known bounds were $-\frac{n^2}{16}$ $-(1+o(1))\frac{n^2}{54}$...