Auditory evoked potentials (AEPs) to click and pure tone stimuli were recorded in unrestrained, unanesthetized rats. The middle latency rat AEPs (N17, P23, N38) had midline scalp distributions similar to human MAEPs and were recorded to within 15 dB above BAEP threshold. In contrast to human MAEPs, rat MAEPs were decreased in amplitude at high stimulation rates and only the N17 component was un...

Thus far, 14 homologues of mammalian Rac proteins have been identified in Dictyostelium. It is unclear whether each of these genes has a unique function or to what extent they play redundant roles in actin cytoskeletal organization. To investigate the specific function of RacB, we have conditionally expressed wild-type (WT-RacB), dominant negative (N17-RacB), and constitutively activated (V12-R...

Ditch samples from AP-4, ER-51 and UK-2 offshore Niger Delta were subjected to biostratigraphic organic geochemical analyses which entail foraminiferal, palynological, Spore Colour Index (SCI), Rock-Eval Pyrolysis Fourier Transform Infrared Spectroscopy (FTIR) analyses. The results have established N19 N17; N17, N16 N15; N9 N8 biozones; P600 P700 palynological zones. dominance of palynomaceral ...

OBJECTIVE Plasma high density lipoprotein (HDL) levels have been shown to be inversely correlated with coronary artery disease, but the mechanisms of the direct protective effect of HDL on endothelial cells (ECs) are not fully understood. In this study, we investigated the role of the HDL-mediated promotion of angiogenesis in human coronary artery ECs (HCECs). METHODS AND RESULTS We developed...

We model core demands for better governance (political, economic and institutional), more employment and less consumer price inflation using a methodological innovation on the complete elimination of cross-country differences in signals susceptible of sparking social revolts. The empirical evidence based on 14 MENA countries show that the Arab Spring was predictable in 2007 to occur between Jan...

Estrogens are known to display significant vasoprotective effects in premenopausal women. PDGF is an important mediator of vascular smooth muscle cell (VSMC) migration and proliferation, and thus atherogenesis. We analyzed the effects of 17beta-estradiol (E2) on beta-PDGF receptor (beta-PDGFR) expression/activation and PDGF-dependent VSMC proliferation, migration, and downstream signaling event...