Psoriatic arthritis has now gained general acceptance as an entity distinct from rheumatoid disease (Garrod and Evans, 1924; McEwen, Ziff, Carmel, DiTata, and Tanner, 1958; Wright, 1961). Distal interphalangeal joint involvement is a prominent feature of psoriatic arthritis (Avila, Pugh, Slocumb, and Winkelmann, 1960; Bauer, Bennett, and Zeller, 1941; Sherman, 1952), but not of rheumatoid arthr...

BACKGROUND Cutaneous T-cell lymphoma can be associated with clinically significant nail alterations, the presentation of which can be protean and misleading. To date, only a few reports have demonstrated direct specific tumor infiltration of the nail bed, while little is known about the efficacy of topical treatments. OBSERVATIONS We describe the case of a 93-year-old man presenting with Séza...

BACKGROUND Psoriasis is a chronic inflammatory skin disease that often progresses with nail alterations. It is suspected that there is a correlation between nail psoriasis and enthesitis of the distal interphalangeal joint, seeming to serve as a predictor. OBJECTIVES To analyze the profile of patients with nail psoriasis and correlate the presence of nail alterations with psoriatic arthritis,...

Yellow nail syndrome (YNS) is a rare entity characterized by a triad of nail changes, lymphoedema and lung involvement. We report a 57-year-old man with rheumatoid arthritis (RA) and YNS. We have reviewed the previous case reports of RA and YNS and discuss the pulmonary manifestations.

Twenty Nail Dystrophy (TND) is a rare acquired idiopathic nail dystrophy characterized by excess longitudinal ridging, distal notching, splitting, loss of nail luster and thinning of nail plates that may affect 1 to 20 nails. It occurs as a common manifestation of various dermatoses affecting the nail unit like lichen planus, psoriasis, atopic dermatitis, onychomycosis, vitiligo and alopecia ar...

Vol. 5 (6D) n June 2005 BACKGROUND (CASE 1) A 41-year-old woman presented with no complaints of pain, but she was concerned about discoloration of her toenails. She has a black belt in karate and works as a karate teacher. She works out in her bare feet and is embarrassed by the condition of her toenails. She had approximately 25% to 30% distal involvement in her toenail, with no other nail inv...

INTRODUCTION: Plaque-type psoriasis affecting the nails, scalp, hands or feet can often be difficult to treat; for example, topical treatments and phototherapy may not penetrate the nail plate or scalp. The objective of this large, international, multicentre study was to investigate the efficacy of efalizumab in a Latin American population of adult patients with moderate-to-severe chronic plaqu...