Type-1 immune responses, mediated by IFNg and TNFaproducing CTLs, Th1, and NK cells, are essential for effective anti-tumor immunity. Despite recent advances in the induction and stabilization of these responses by cancer immunotherapies, the clinical success of these approaches remain limited. Here, we report that the activation of type-1 immunity within the human tumor microenvironment (TME) ...

In Burkina Faso, women make up nearly 52% of the population, but they account for less than 20% business start-ups. This paper seeks to identify factors that explain entrepreneurial intent Burkinabe women. It is based on socio-cognitive career theory and a quantitative approach involving sample 935 The results multinomial logistic regression show five variables (perception skills, fear failure,...

Andrea Mazzolini, Marco Gherardi, 3 Michele Caselle, Marco Cosentino Lagomarsino, 3, 4 and Matteo Osella∗1 Physics Department and INFN, University of Turin, via P. Giuria 1, 10125 Turin, Italy Sorbonne Universités, UPMC Univ Paris 06, UMR 7238, Computational and Quantitative Biology, 15 rue de l’École de Médecine Paris, France CNRS, UMR 7238, Paris, France FIRC Institute of Molecular Oncology (...

1Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4 2Center for Reproductive Medicine and Andrology, University of Münster, Domagkstraße 11, 48149 Münster, Germany 3Department of Obstetrics/Gynecology & Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA 4Department of...

Commonwealth Scientific and Industrial Research Organization Plant Industry, P.O. Box 1600, Australian Capital Territory 2601, Australia (S.R., Z.L., B.K.H., S.A., M.K.M.); Plant Breeding Institute, University of Sydney, Cobbitty, New South Wales 2570, Australia (A.R.); Department of Biological Sciences, Osaka Kyoiku University, 4–698–1 Asahigaoka, Kashiwara, Osaka 582, Japan (Y.M.); and Kansai...

Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA, Department of Clinical Genetics, Helsinki University Central Hospital, Haartman Institute, Department of Medical Genetics, University of Helsinki, Helsinki, Finland and Department of Epidemiology, Graduate School of Public Health, University of Pittsbur...