Background Single Molecule Biophysics (SMB) represents one of the fastest-developing and most advanced fields of application for nanopositioning, with extreme requirements for positioning performance, stability and synchronization Significant recent advancements in SMB instrumentation and other sub-nanoscale endeavors benefit from leveraging new interfacing technologies offering fast speeds and...

In this article, the resolution of a nanopositioning system is defined as the smallest distance between two non-overlapping points. Techniques are then described for estimating the closed-loop resolution from time-domain recordings of the contributing noise sources. Practical guidelines are also discussed to ensure statistically valid estimates. Experimental results show that the resolution of ...

Nanopositioning technology is widely used in high-resolution applications. It often uses piezoelectric actuators due to their superior characteristics. However, exhibit a hysteresis phenomenon that limits positioning accuracy. To compensate for the effect, developing an accurate model of very important. This task challenging, requiring some considerations multivalued mapping loops and generaliz...