Extensive consumer exposure to food- and cosmetics-related consumer products containing nanosilver is of public safety concern. Therefore, there is a need for suitable in vitro models and sensitive predictive rapid screening methods to assess their toxicity. Toxicogenomic profile showing subtle changes in gene expressions following nanosilver exposure is a sensitive toxicological endpoint for t...

STATEMENT OF THE PROBLEM Nanosilver particles have the potential to serve as a bactericidal agent because of the inherent antimicrobial influences of silver ion. The literature confirmed that specific micro-organisms, especially streptococci, have an important role as an etiological factor for caries. PURPOSE The aim of this study was to evaluate the antimicrobial effect of conventional and n...

Nanosilver particles are used in various clinical settings because of their antibacterial properties. However, their safety evaluation when used for gynaecological disorders has not been established. Nanosilver particles were administrated in the vagina of New Zealand rabbits, and the pathological appearance of the surrounding tissue was examined by hematoxylin-eosin staining and transmission e...

BACKGROUND Various materials have been added to mineral trioxide aggregate to enhance its properties. This study was aimed to compare the sealing efficacy of MTA with and without nanosilver using bacterial leakage approach. MATERIAL AND METHODS Seventy canine teeth were prepared and obturated. Then, after apical resection, the root-end cavities were prepared by ultrasonic retrotips. Teeth wer...

Silver and gold have been used for centuries as antimicrobial agents. The aim of the study was to investigate diametral tensile strength, microhardness, ion release and light transmission of experimental resin composites. Flowable dental composite SDR (Dentsply, United Kingdom) was modified by nanogold, nanosilver and silica addition. The metal ion release, light transmission study, microhardne...

The aim of the present study was to elucidate the biological effectiveness and character of a nanosilver-epidermal growth factor (EGF) sustained-release carrier. This was synthesized using the self-assembly method and then characterized by transmission electron microscopy and UV spectrophotometry. The biological activity of the sustained release carrier was determined through cytological, bacte...

OBJECTIVES Residual microorganisms in the root canal system (RCS) after endodontic therapy such as Candida albicans are a major cause of endodontic failure. Calcium hydroxide (CH) and chlorhexidine (CHX) have suitable antimicrobial activity against bacteria and can be used as intracanal medicaments. Nanosilver has also shown antimicrobial activity against microorganisms. This study aimed to com...

AIM The aim was to evaluate the antibacterial properties of composite resin containing nanosilver against Streptococcus mutans (SM) and Lactobacillus (L). MATERIALS AND METHODS Nanosilver was added to Z250 composite at 0.5 and 1% by weight. In order to confirm the homogenous distribution of the nanoparticles in the composite resin, SEM-EDX analysis was performed on one sample in each group. Z...

The aggregation kinetics of silver nanoparticles (AgNPs) that were coated with two commonly use agents—citrate and polyvinylpyrrolidone (PVP)—were investigated. Time-resolved dynamic light (DLS) was employed to measure the aggregation kinetics of the AgNPs over a range of monovalen electrolyte concentrations. The aggregation behavior of citrate-coated AgNPs in NaCl was in excel with the predict...