The aim of this study was to determine whether polymorphisms of the glucocorticoid receptor gene, influencing glucocorticoid sensitivity, are associated with persistent nasal carriage of Staphylococcus aureus. Two nasal swab cultures were obtained from each of 2,929 participants. Subjects were classified as persistent carriers (n=563) if both cultures were positive. GG homozygotes of the exon 9...

Untreated heavy nasal carriers of staphylococci have been reported to have staphylococci on their skin more frequently and to disseminate staphylococci in the air in larger numbers than either noncarriers or carriers of smaller numbers of these bacteria (1). If the nose is the main source of skin and aerial staphylococci, suppression of nasal staphylococci should be followed by a reduction in b...

OBJECTIVE To evaluate the prevalence and transmission of methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization, as well as risk factors associated with MRSA carriage, among residents of a long-term care facility (LTCF). DESIGN Prospective, longitudinal cohort study. SETTING A 100-bed Veterans Administration LTCF. PARTICIPANTS All current and newly admitted residents of the...

methods in a cross-sectional study, 164 adult patients who were admitted to the icu of a teaching hospital were screened for nasal and extra-nasal carriage of mrsa. in addition, the icu-hospitalized patients were evaluated for mrsa acquisition during their icu stay. results out of the 164 patients admitted to the icu, 12 (7.3%) patients were methicillin-susceptible staphylococcus aureus (mssa) ...

background and objectives: staphylococcus aureus ( s. aureus ) nasal carriage may be responsible for some serious infections in hemodialyzed patients. the main target of this study was to estimate the prevalence of s. aureus nasal carriage in hemodialysis outpatients and medical staff in hemodialysis centers specifically in fez region. the second target is to identify the risks of colonization,...

We screened 14,008 adult nonsurgical patients for Staphylococcus aureus nasal carriage at hospital admission and assessed them for invasive S. aureus disease and in-hospital mortality. Multilocus sequence typing was performed on endogenous invasive strains and nasal strains of matched asymptomatic carriers to investigate whether virulent clones could be identified in nasal carriers. Clonal comp...

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to most antibiotics and is an important pathogen of nosocomial infections. The prevalence of community (CA-MRSA) and hospital acquired methicillin-resistant S. aureus (HA-MRSA) infection is increased. In this study we investigated the frequency of MRSA colonization and its antibiotic susceptibility in students of Rafsan...

BACKGROUND Persistent carriers have a higher risk of Staphylococcus aureus infections than noncarriers but a lower risk of bacteremia-related death. Here, the role played by anti-staphylococcal antibodies was studied. METHODS Serum samples from 15 persistent carriers and 19 noncarriers were analyzed for immunoglobulin (Ig) G, IgA, and IgM binding to 19 S. aureus antigens, by means of Luminex ...

Background: The aggravating role of Staphylococcus aureus is well known in atopic dermatitis but has not yet been proven in psoriasis. The role of Staphylococcus aureus superantigens is emphasized in the initiation, maintenance and complications of psoriasis. We investigated the frequency of nasal, axillary, and perineal carriage of Staphylococcus aureus (SA) in patients with psoriasis and its ...