Nasal polyps are usually associated with inflammation, allergy or mucoviscidosis. The global burden of patients COVID-19 infection, including that in the Indian sub-continent,is still very high and they at an increased risk developing invasive fungal infections probably due to their immunocompromised state. Here, we review 4 cases nasal polyposis ongoing past history infection without co-morbid...

OBJECTIVE To demonstrate the long-term efficacy of intranasal furosemide, an inhibitor of the sodium chloride cotransporter channel at the basolateral surface of the respiratory epithelial cell, vs no therapeutic intervention vs intranasal mometasone furoate, a corticosteroid, in preventing relapses of chronic hyperplastic sinusitis with nasal polyposis. DESIGN Randomized prospective controll...

A 17-year-old female with allergic fungal sinusitis and nasal polyposis presented with epistaxis in the emergency room. On examination, right-sided proptosis and irregular nasal obstruction were observed in the right nasal cavity. CT imaging revealed massive right-sided polyposis and significant ipsilateral malformation with boney architecture preservation of the ethmoidal labyrinth and lamina ...

Introduction: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a relatively common disease with serious impacts on patient quality of life. Recurrence of polyps after functional endoscopic sinus surgery (FESS) is a dilemma. Vitamin D3 (VD3) is known to inhibit the proliferation of nasal polyp-derived fibroblasts. The present study aimed to investigate the effects of oral VD3 on the...

Background: Non-allergic rhinitis is a disease that is often trivialised, leading to inadequate management and unnecessary costs. One of the most common types of severe non-allergic nasal inflammation is nasal polyposis. Nasal polyposis is associated with asthma. The aims of this thesis were to estimate the prevalence of self-reported non-allergic nasal symptoms and explore relations of these s...

Nasal polyposis is a severe, chronic inflammatory condition of the paranasal sinuses and is frequently associated with asthma and aspirin sensitivity. Mesenchymal stem cells exhibit a potent immunosuppressive effect in several inflammatory conditions, and their role in nasal polyposis remains little explored. Hence, we investigated whether bone marrow-derived mesenchymal stem cells could modula...