In patients with nonalcoholic steatohepatitis (NASH), the prevalence of cirrhosis is higher among women than men, and hepatocellular carcinoma (HCC) develops mainly in the cirrhotic stage among women. However, the long-term outcomes in female patients with NASH have not been fully elucidated, and age, gender and BMI were not simultaneously adjusted in previous studies on the prognosis of NASH. ...

BACKGROUND The changes in the liver in nonalcoholic fatty liver disease (NAFLD) range over a wide spectrum, extending from steatosis to steatohepatitis (NASH). However it has remained difficult to differentiate between NASH and non-progressive NAFLD on the basis of the clinical findings alone. AIMS In this study we investigated the clinical usefulness of plasma Pentraxin3 (PTX3) levels to pre...

The morphological features of nonalcoholic fatty liver disease (NAFLD) range from steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Liver biopsy remains the main tool for NASH diagnosis and many histological systems to diagnose and grade NAFLD were proposed. We evaluated the relationship among NAFLD activity score (NAS), histological diagnoses (non-NASH, possible NASH, and definit...

In this paper, bi-matrix games are investigated based on L-R fuzzy variables. Also, based on the fuzzy max order several models in non-symmetrical L-R fuzzy environment is constructed and the existence condition of Nash equilibrium strategies of the fuzzy bi-matrix games is proposed. At last, based on the Nash equilibrium of crisp parametric bi-matrix games, we obtain the Pareto and weak Pareto...

BACKGROUND Non-alcoholic fatty hepatitis (NASH) is highly prevalent, mitochondria damage is the main pathophysiological characteristic of NASH. However, treatment for mitochondria damage is rarely reported. METHODS NASH model was established in rats, the protective effects of curcumin were evaluated by histological observation; structure and function assessments of mitochondria; and apoptotic...

In this paper we show that some decision problems regarding the computation of Nash equilibria are to be considered particularly hard. Most decision problems regarding Nash equilibria have been shown to be NP-complete. While some NP-complete problems can find an alternative to tractability with the tools of Parameterized Complexity Theory, it is also the case that some classes of problems do no...