background: inflammatory myofibroblastic tumor (imt) is a tumor composed of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. the most common sites of involvement include the lung, liver and orbit, but it has been reported to occur in nearly every site of the body, including oral cavity and soft tissue. although common in other sites, such a tumo...

a field study was conducted to evaluate the effect of haloxyfop-r-methyl ester doses in different grass weeds in various growing stages in safflower during 2011-2012 growing season in research farm of college of agriculture, shiraz university. the study was carried our as split split plot based on randomized complete block design with three replicates. the main factor, sub factor and sub sub fa...

We examined first evidence for the significance of SALL4, a transcription factor essential for embryonic development and the self-renewal of embryonic stem (ES) cells, as a natural resistance factor against anticancer drugs in lung cancer. To determine the significance of SALL4 expression in lung cancer cells, small inhibitory RNA (siRNA) against SALL4 was transduced into A549 and SBC-3 cells, ...

Breast cancer is the most common malignancy among American women. Due to increased screening, the majority of patients present with early-stage breast cancer. The Oxford Overview Analysis demonstrates that adjuvant hormonal therapy and polychemotherapy reduce the risk of recurrence and death from breast cancer. Adjuvant systemic therapy, however, has associated risks and it would be useful to b...

The complexity of tumor histomorphology reflects underlying tumor biology impacting on natural course and response to treatment. This study presents a method of computer-aided analysis of tissue sections, relying on multifractal (MF) analyses, of cytokeratin-stained tumor sections which quantitatively evaluates of the morphological complexity of the tumor-stroma interface. This approach was app...

An increasing number of studies have demonstrated the effectiveness of flagellin (FliC) as an adjuvant. In this study, FliC(s) from Salmonella enterica serovar Typhimurium, Pseudomonas aeruginosa, and Escherichia coli were compared. In silico studies were designed to determine physicochemical parameters of FliC from different bacteria. The fliC gene corresponding to best model was amplified, cl...

CD8+ cytotoxic T lymphocytes confer protection against infectious diseases caused by viruses, bacteria, and parasites. Hence, significant efforts have been invested into devising ways to generate CD8+ T cell-targeted vaccines. Generation of microbe-free protein subunit vaccines requires a thorough knowledge of protective target antigens. Such antigens are proteolytically processed peptides pres...

influenza is a contagious viral disease that is seen in avian, human and other mammals, so its control is important. vaccination against influenza virus subtype h9n2 is one of the ways in controlling program, for this reason several vaccines has been produced. recently, application of inactivated oil-emulsion vaccines in poultry for controlling low pathogenic avian influenza is increasing. at p...