Purpose: To determine the dose – toxicity profile of the aqueous extract of Nauclea latifolia stem bark (AQE). Methods: Oncin France Souche A (OFA) rats were orally administered with AQE at doses of 1.8, 18 and 180 mg/kg body weight for 28 days. In parallel, oral acute toxicity test in Swiss mice was performed with AQE at doses of 2, 4, 8 and 18g/kg body weight. Blood, urine and other biochemic...

The purpose of this study is to identify a list medicinal plants used by Traditional Medicine Practitioners and the populations treat malaria anemia in health district Korhogo1. ethnobotanical survey carried out among 251 people, including 51 practitioners traditional medicine 200 people from general population identified 49 species for treatment malaria. Individuals cited Azadirachta indica 54...

AIM OF STUDY The ethnobotanical study surveyed the different types of medicinal plants used for the treatment of malaria in the south-western region of Nigeria. MATERIALS AND METHODS Information was collected by interviewing indigenous people, using a semi-structured questionnaire. Collected plant samples were identified and authenticated in Forestry Research Institute of Nigeria, Ibadan, Nig...

Tramadol, previously only known as a synthetic analgesic, has now been found in the bark and wood of roots of the African medicinal tree Nauclea latifolia. At present, no direct evidence is available as to the biosynthetic pathway of its unusual skeleton. To provide guidance as to possible biosynthetic precursors, we have adopted a novel approach of retro-biosynthesis based on the position-spec...

In Africa, up to 80% of the population relies on herbal concoctions for their primarily health care. In Togo, western Africa, Tem tribe is a population with old knowledge of medicinal plants, however, still very little is known about their medical practices. The present study was conducted to access for the apprehension of adverse effects of traditional remedies by Tem traditional healers (TH)....

Abstract The Nok culture in central Nigeria, dated 1500–1 cal bc , is known for its famous terracotta sculptures. We here present a study on > 11,000 botanical macro-remains from 50 sites, including 343 samples contexts and 22 dating between ad 100 400, after the end of culture. With 9,220 remains, pearl millet ( Cenchrus americanus (L.) Morrone, syn. Pennisetum glaucum R.Br.) dominant sampl...