PURPOSE Prostate biopsy for diagnosing cancer can be painful. The efficacy and safety of combination perianal-intrarectal lidocaine-prilocaine (PILP) cream and periprostatic nerve block were compared with nerve block alone during transrectal ultrasound guided prostate biopsy (TRUS-Bx). MATERIALS AND METHODS From October 2007 to August 2009, 74 men undergoing a transrectal prostate biopsy were...

versa can also happen. However, the co-existence of a patch of morphea mimicking as Leprosy patch in an underlying case of neuriticleprosy, can be very misleading. We present a case with glove and stocking anaesthesia and peripheral nerve enlargement with a single large hypopigmented, non-anaesthetic macule on trunk, clinically diagnosed as Hansen's disease (Borderline Tuberculoid BT). Slit ski...

OBJECTIVES We aimed to determine whether ranirestat, an aldose reductase inhibitor, maintains the improved nerve function observed in patients with diabetic sensorimotor polyneuropathy (DSP) after completing a 12-week nerve biopsy study. RESEARCH DESIGN AND METHODS Patients with mild to moderate DSP, as determined by the presence of sural nerve responses, were enrolled in a double-blind, plac...

BACKGROUND AND AIM Transrectal ultrasound (TRUS) -guided prostate biopsy is often a painful procedure. The aim of this study was to evaluate the effectiveness of combining oral paracetamol and codeine with periprostatic nerve block in relieving prostate biopsy-related pain. MATERIAL AND METHODS In this prospective study we compared the pain associated with prostate biopsy between two groups o...

An 8-year-old girl presented with progressive painless right peroneal and tibial nerve palsy. A 20-year-old woman had insidious weakness of the left wrist and fingers extension. Both underwent neurophysiology (tables e-1 through e-4 on the Neurology® Web site at Neurology.org) and nerve ultrasound that showed enlargement of sciatic (figure, A) and radial nerve (figure, D–E). A 3D–magnetic reson...

A 48-year-old man with hypertension, hyperlipidemia, and hypothyroidism presented to an outside institution progressive bilateral lower extremity numbness weakness. Nerve conduction studies (NCS) suggested acquired demyelinating polyneuropathy. Right sural nerve biopsy revealed mild chronic neuropathy, axonal degeneration, demyelination, remyelination. He received monthly IV immunoglobulin (IVI...