نتایج جستجو برای: neural differentiation

تعداد نتایج: 515348  

Journal: :iranian journal of veterinary medicine 2010
mir sepehr pedram محمد مهدی دهقان masoud soleimani davood shafii seyed marjanmehr

in the bone marrow, there are certain populations of stem cell sources with the capacity to differentiate into several different types of cells. ideally, cell transplants would be readily obtainable, easy to expand and bank, and capable of surviving for sufficient periods of time. bone marrow mesenchymal stem cells (bm-mscs) possess all of these characteristics. one of the most important benefi...

Journal: :iranian biomedical journal 0
محمدرضا نیک روش mohammad reza nikravesh مهدی جلالی mehdi jalali علی رضا فاضل ali reza fazel

during early neurogenesis, the floor plate plays an essential role(s) in the differentiation of the ventral portion of neural tube. in this study, we detected the specific distribution of unique glycoconjugate during the floor plate differentiation. formalin fixed paraffin sections of balb/c mice (10-14 embryonic days) were processed for histochemical studies using horseradish peroxidase-labell...

Journal: :cell journal 0

objective: ecstasy, or 3, 4 (±) methylenedioxymethamphetamine (mdma), is a potent neurotoxic drug. one of the mechanisms for its toxicity is the secondary release of glutamate. mouse embryonic stem cells (mescs) express only one glutamate receptor, the metabotropic glutamate receptor 5 (mglu5), which is involved in the maintenance and self-renewal of mescs. this study aims to investigate whethe...

Journal: یافته 2009
alireza Khalatbari , taghi Tarihi ,

Background: This article reviews experimental and clinical studies in which neural injuries repaired with bone marrow stromal cells. History: Bone marrow contains two kinds of stem cells: hematopoietic and nonhematopoietic (stromal) stem cell. In vitro studies indicate that bone marrow stromal cells have the capacity of differentiation into other cells (such as neural cell) under treatment wit...

Journal: :avicenna journal of medical biotechnology 0

background: peroxisome proliferator activated receptor gamma (pparγ), a member of nuclear receptor superfamily, comprises two isoforms in mouse. these two isoforms are encoded by different mrnas, which are arisen by alternative promoter usage. there are two promoter regions upstream of pparγ gene. a 3 kb fragment, containing several transcription factor binding sites, acts as pparγ1 promoter re...

Journal: :iranian journal of veterinary research 2015
t. peirouvi f. yekani m. azarnia m. massumi

hippocampal neural stem/progenitor cells (hipp-ns/pcs) of the adult mammalian brain are important sources of neuronal and gial cell production. in this study, the main goal is to investigate the plasticity of these cells in neuronal/astroglial differentiations. to this end, the differentiation of the hipp-ns/pcs isolated from 3-month-old wistar rats was investigated in response to the embryonic...

Journal: :Proceedings of the National Academy of Sciences 1996

آی, جعفر, ابراهیمی باروق, سمیه, رحیمی, اعظم, کوچصفهانی, هما محسنی,

Background: Small molecule Purmorphamin (PMA) is the agonist of smoothened protein in Sonic hedgehog (Shh) signaling pathway. Effect of purmorphamin small molecule on differentiation of mesenchymal cells into bone tissue has been studied previously. Use of Shh causes progression of neural differentiation, and the differentiated cells express specific neural markers. Neurofilament (NF) and acety...

بهاروند, حسین, زارع مهرجردی, نرگس, نعمتی, شیوا,

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Neural stem cells are undifferentiated cells that are located in limited areas of central nervous system. These cells have proliferation and self-renew ability and can be differentiated into neurons and glial cells. Mature nerve cells do not have proliferative ability; and due to the limited number of nerve stem cells, injuries to the nervous system are not recoverable. The purpose of this revi...

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