Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. Ionic conductances regulate T cell activation as well as neuronal function and thus have been found to play a crucial role in MS pathogenesis. Since present therapeutical approaches are only parti...

#### Notable in Neurology This Week issue features an article that explores racial and ethnic disparities the rate of thrombolytic declination among patients with acute ischemic stroke; another evaluates long-term cognitive function socioprofessional attainment people pediatric-onset multiple sclerosis. A featured Historical discusses Jean-Louis Prévost's contributions to study oculomotor funct...