INTRODUCTION Neuroendocrine tumours of the colon and rectum are infrequent. They are usually undifferentiated, easy to diagnose for the pathologist and are especially aggressive in their clinical behaviour. Prognosis is usually poor and they have a high tendency to metastase early. MATERIAL AND METHODS We have reviewed our experience in a Colorectal Unit during a period of six years. Patients...

The measurement of general and specific biochemical markers in patients with neuroendocrine tumours assists with diagnosis and gives an indication of the effectiveness of treatment and they may be used as prognostic indicators. There is much agreement that chromogranin A is the most universally helpful marker; it is found to be elevated in the circulation of about 90% of patients with metastati...

UNLABELLED A 33-year-old male was diagnosed with a metastatic neuroendocrine carcinoma of uncertain primary. He defaulted from follow-up without therapy and some months later developed episodic severe hypoglycaemia, which was found to be associated with inappropriately elevated insulin and C-peptide levels. It was considered likely that the neuroendocrine tumour was the source of the insulin se...

Neuroendocrine tumours are rare in the gynaecologic tract, comprising approximately 2% of all gynaecological tumours. They have an aggressive behaviour and are a diagnostic and clinical challenge, due to their rarity and the lack of standardized therapeutic approaches. There are a few case reports. It is defined as a high-grade carcinoma exhibiting neuroendocrine differentiation. The authors de...

Neuroendocrine tumours (NETs) are thought to arise from multipotent stem cells of the diffuse neuroendocrine system. The incidence is reported as 2.5-5 cases per 100 000 population and the incidence is rising. NETs are generally low grade indolent tumours however; the histological spectrum varies from low grade well differentiated tumours to high grade poorly differentiated tumours. A number of...

Objective: To report an extremely rare case of neuroendocrine tumour with simultaneous involvement of both the facial nerve and the deep lobe of parotid gland. Method: case report and English language literature review concerning neuroendocrine neoplasm involving the facial nerve with emphasis on clinical presentation. Results: We report a unique case of adenoma with neuroendocrine differentiat...