نتایج جستجو برای: neuromuscular blockade
تعداد نتایج: 62474 فیلتر نتایج به سال:
BACKGROUND AND OBJECTIVES The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental studies and in humans. The aim of this study was to evaluate in vitro the interaction between ropivacaine and pancuronium, the influence on tran...
AANA Journal June 2009 Vol. 77, No. 3 219 Sugammadex sodium is the generic drug name for the novel modified gamma cyclodextrin that terminates neuromuscular blockade induced by aminosteroidal neuromuscular blocking agents. Published phase II and phase III clinical data support preclinical and clinical phase I study findings of fast, safe, and efficacious reversal of all levels of neuromuscular ...
Vecuronium was used as the only neuromuscular blocking agent in 81 paediatric patients (neonates to adolescents) during fentanyl and nitrous oxide anaesthesia. The thenar electromyogram was used to monitor neuromuscular blockade. Neonates and infants had a mean requirement of vecuronium 105 micrograms kg-1 during the first 1 h of anaesthesia, to establish and maintain 90-98% neuromuscular block...
BACKGROUND This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocation to sugammadex (2 or 4 mg kg(-1)) or usual care (neostigmine/glycopyrrola...
The relationship between the time of onset of neuromuscular blockade and the time at which laryngoscopy was attempted was studied in patients presenting for emergency obstetric or emergency general surgical procedures. "Train-of-four" stimulation and visual observation of the evoked twitch response in the hand were used as a measure of the degree of neuromuscular blockade. The attendant anaesth...
We describe the case ofa 2.5 kg weighing infant with Larsen syndrome that we used sugammadex for reversal of deep neuromuscular blockade. Sugammadex was superior to classical reversal agent neostigmine because of the effect on deep neuromuscular blockade and less side effects. Our patient had cervical instability, small for age and also entubation difficulty with facial anomaly. We discussed th...
A significant reduction was noticed in the amount of vecurenium needed to maintain steady neuromuscular blockade at 20% twitch height (Tl> in patients given nicardipine intraoperatively. Bolus ajection of either nicardipine or d.iltlazem during constant infusion of yecuronium produced transient depression of Tl and the train-offour ratio CTOFR). Reversal of neuromuscular blockade wtth a choline...
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