Insights into the process of HIV-1 neutralization may assist rational vaccine design. Here, we compared antibody neutralization against the JR-FL primary isolate and trimer binding affinities judged by native PAGE. Monovalent Fab-trimer binding and neutralization showed a direct quantitative relationship, implying that neutralization begins as each trimer is occupied by one antibody. At saturat...

Generally, trace precious metals remaining in wastewaters generated from the refining process of precious metals are not recovered, due to a relatively high processing cost as well as various technical problems. Recovery of precious metals from wastewaters is very important for the conservation of resources and the protection of environment. However, wastewaters containing a large amount of amm...

The performance of a Model Predictive Control (MPC) algorithm depends on the quality of the derived model. Using a divide-and-conquer strategy process operations were partitioned into several operating regions and within each region, a local linear model was developed to model the process. This set of locally linearized models was simply and effectively combined into a global description of a m...

In this work, the pH neutralization process is described by a neural network Wiener (NNW) model. A nonlinear Model Predictive Control (NMPC) is established for the considered process. The main difficulty that can be encountered in NMPC is solving the optimization problem at each sampling time to determine an optimal solution in finite time. The aim of this paper is the use of global optimizatio...

a comprehensive study on the chemical composition of rainwater was carried out in obuasi, a gold mining town in ghana. rainwater samples were analyzed for major ions (ca2+,mg2+, k+, na+, nh4+, cl-, no3- and so4 2-) and trace metals (fe, al, zn, pb, cr, and cd). the rainwater was typically acidic with a mean ph of 4.76±0.47, which ranged from 4.0 to 5.6. the low ph found in the water suggests t...

measles is one of the most contagious human diseases. although mass vaccination programs have reduced the incidence of this disease, measles is still an important cause of morbidity and mortality among children in developing countries. therefore the use of sensitive techniques to evaluate vaccine efficacy and level of immunity among members of susceptible communities is crucial. serum neutraliz...

 An adaptive input-output linearization method for general nonlinear systems is developed without using states of the system. Another key feature of this structure is the fact that, it does not need model of the system. In this scheme, neurolinearizer has few weights, so it is practical in adaptive situations.  Online training of neuroline...