Massive pulmonary hemorrhage (MPH) in newborn infants is a catastrophic event with a fatal result. The aim of this study was to assess the efficacy of high frequency oscillatory ventilation (HFOV) as a rescue therapy for MPH in newborn infants. Eighteen newborn infants with MPH refractory to conventional mechanical ventilation were treated with HFOV. Changes in oxygenation were assessed using a...

Cerebral infarction of newborn infants is a rare condition. It remains the least predictable etiology of neonatal seizures, and the appreciation of its occurrence among physicians needs to be re-addressed. The most common presenting feature is seizure. We report 2 full term newborn infants who developed middle cerebral infarction. These infants presented primarily with ischemic limbs for severa...

Introduction The regulation of oxygen delivery to acutely ill infants requiring mechanical ventilation is a vital process in neonatal intensive care medicine. We have designed a microcomputer based system to automatically and continuously control the inspired oxygeff-" concentration (FI02) delivered mechff~ically ventilated newborn infants. In addition, we will utilize this computer platform to...

BACKGROUND AND OBJECTIVE Vitamin B(6) plays a pivotal role in brain development and functioning. Differences in vitamin B(6) homeostasis between preterm and term newborn infants have been reported. The authors sought to investigate whether B(6) vitamers in cerebrospinal fluid (CSF) of preterm and term newborn infants are different. METHODS B(6) vitamer concentrations were determined in 69 CSF...

Several pathological changes affect the eyes of newborn infants, one of the most important ofwhich is retrolental fibroplasia. The object of developing retinal photography in the newborn was to record the appearance of blood vessels in premature infants who are at risk of developing retrolental fibroplasia. In addition it has proved possible to record the normal appearance of the newborn fundus...

Leptin is an adipocyte-derived peptide hormone regulating energy balance in experimental animals. Although the physiological function of leptin in humans is still unclear, its secretion is closely related to fat mass in adult humans. To examine how fetal growth correlates with leptin levels at birth, an umbilical cord venous blood sample was obtained at the delivery from 50 term newborn infants...

Several pathological changes affect the eyes of newborn infants, one of the most important ofwhich is retrolental fibroplasia. The object of developing retinal photography in the newborn was to record the appearance of blood vessels in premature infants who are at risk of developing retrolental fibroplasia. In addition it has proved possible to record the normal appearance of the newborn fundus...

OBJECTIVE To determine the incidence of haemorrhagic disease of the newborn in the British Isles, study risk factors, and examine the effect of vitamin K prophylaxis. DESIGN Prospective survey of all possible cases of haemorrhagic disease of the newborn as reported by consultant paediatricians using the monthly notification cards of the British Paediatric Surveillance Unit and a follow up que...