Granulocyte colony-stimulating factor (G-CSF) in the cerebrospinal fluid from patients with meningitis was measured by our modified enzyme-linked immunosorbent assay for G-CSF. The minimal detection level was 20 pg/mL G-CSF. In patients with bacterial meningitis, the G-CSF levels in the cerebrospinal fluid were extremely elevated, showing a mean value of approximately 1,500 pg/mL. On the other ...

C-reactive protein was evaluated in the cerebrospinal fluid of 250 patients to determine if its measurement is of any clinical value in the diagnosis of bacterial meningitis. The C-reactive protein was found to be significant in the diagnosis of bacterial meningitis.

Investigation of 67 patients with neurological disorders (excluding meningitis) showed a mean level of Mg in cerebrospinal fluid of 1.93 +/- 0.03 mEq./l. These figures are significantly lower than earlier figures published in the literature. Patients with polyradiculo-neuritis do not show the fall in cerebrospinal fluid Mg levels reported in cases of infective meningitis. The level of Mg in cer...

Introduction: Congenital anomalies of the cochlea and labyrinth can be associated with meningitis and varying degrees of hearing loss or deafness. Despite antibiotics, meningitis remains a life threatening complication.   Case Report: We report a case of recurrent meningitis following episodes of otitis media in a cochlear implantee child with bilateral vestibulocochlear malformation, due to f...

how to cite this article: khosroshahi n, alizadeh p, khosravi m, salamati p, kamrani k. spinal fluid lactate dehydrogenase level differentiates between structural and metabolic etiologies of altered mental status in children. iran j child neurol. 2015 winter;9(1):31-36. abstract objective altered mental status is a common cause of intensive care unit admission in children. differentiating struc...

Thirty-six patients with coliform meningitis in the 15-year period 1960-1974 are reported. Only 9 patients survived unscathed though the other 5 survivors were not seriously affected. During the septicaemic phase of the illness the cerebrospinal fluid (CSF), though positive on culture, may be otherwise normal. Meningitis can ensue even when the patient is receiving antibiotics to which the orga...

Enterobius vermicularis is a nematod of large intestine in man. Extra intestinal localization of this parasite is rare. A 60 year old man was admitted to the hospital with the clinical manifestation of meningitis. In laboratory examination of cerebrospinal fluid (C.S.F), the appearance was red, Albu-min level was high and the glucose showed normal value. Haematoxylin and Eosin stained slides pr...

Background: Bacterial meningitis in the newborn is globally renowned for high mortality. The associated morbidities also include audiologic, motor, visual and mental deficits. Objective: To highlight the peculiarities in the current diagnostic and management strategies in newborn meningitis. Methods: Relevant literature on the subject published only in English language or translated to English ...

The influence of methylprednisolone on the passage of ampicillin and gentamicin into and activity within cerebrospinal fluid was examined in two models of experimental meningitis. Steroid pretreatment reduced the concentrations of these drugs in purulent cerebrospinal fluid of rabbits with experimental pneumococcal and Escherichia coli meningitis (P less than 0.05). However, the resultant mean ...

Lactic acid concentration was determined in 37 specimens of cerebrospinal fluid by gas liquid chromatography. It was found to be raised ( ~ 30 mg/dl) in 15 specimens from culture positive cases of bacterial meningitis and one of fungal meningitis. It was < 30 mg/dl in cerebrospinal fluid from four cases of viral meningoencephalitis and 10 contaminated specimens. It was also raised in two specim...