We have studied the effect of human bacterial pathogen Neisseria gonorrhoeae (Ngo) on the activation of nuclear factor (NF)-kappaB and the transcriptional activation of inflammatory cytokine genes upon infection of epithelial cells. During the course of infection, Ngo, the etiologic agent of gonorrhea, adheres to and penetrates mucosal epithelial cells. In vivo, localized gonococcal infections ...

Disability is a common occurrence in many countries and a subject of much discussion and lobby. People with disability (PWD) are frequently segregated in society and by-passed for many opportunities. Stigma hinders their potential contribution to society. Doctors with Africa CUAMM, an Italian NGO, started a project to improve the life of PWD in the West Nile region in northwestern Uganda in 200...

BACKGROUND Since December 2011, a non-governmental organization (NGO) has been associated with our clubfoot clinic. Debates related to the effectiveness of NGOs in clinical milieu have raged on for a long time. The aim of this study was to analyze the effectiveness of an NGO in supporting the running of a clubfoot clinic in a tertiary care center. METHODS A descriptive, observational study wa...

In this paper we explore the strengths and gaps among NGO surveys based on an analysis of the records held in the CE-DAT database at CRED. We conclude by recommending the priority areas for strengthening NGO capacity to undertake surveys and ways to improve data quality in general.

The multifunctional DNAzyme (Dz) delivery system is developed based on nano-sized graphene oxide (nGO) for simultaneous detection and knockdown of the target gene. The Dz/nGO complex system allowed convenient monitoring of HCV mRNA in living cells and silencing of the HCV gene expression by Dz-mediated catalytic cleavage concurrently.

Removal of contaminants from wastewater is one key element for the development sustainable society. Here, innovative “all-lignocellulose” derived photo-curable hydrogel nanocomposites based on methacrylated carboxymethyl cellulose (M-CMC) and lignosulfonate-derived carbonaceous products were successfully designed. The carbon synthesized by microwave-assisted hydrothermal carbonization (MAHC), f...

Introduction: Colon carcinoma is one of the most common form of cancer that affects the health and lives of people. 5-Fluorouracil (5-Fu) has become useful as synergistically therapy with other antitumor agents in a colon cancer therapy. Short half-life, wide distribution and different side effects of 5-Fu limit its medical applicability. In this study, we have investigated the...