[PO4]3? possesses small microscopic second-order susceptibility and polarizability anisotropy, which inherently result in weak second-harmonic generation (SHG) birefringence. Herein, a new noncentrosymmetric phosphate, [C(NH2)3]3PO4·2H2O, was successfully designed synthesized by solution evaporation method. [C(NH2)3]3PO4·2H2O without metal ions is composed of planar conjugated guanidine cations...

The MOFs selected in this work are NH2-MIL-53(Al), MIL-100(Fe) and UiO-66 type (Zr-BDC NH2-Zr-BDC). We have tried to assist the sustainable synthesis of MOFs, at room temperature water as a solvent, with presence non-ionic surfactants: Pluronic F127 P123. parent prepared solvent commonly grow form agglomerates small crystallites all cases. X ray diffraction patterns surfactant templated NH2-MIL...

All known naturally occurring linear cationic peptides adopt an amphipathic alpha-helical conformation upon binding to lipids as an initial step in the induction of cell leakage. We designed an 18-residue peptide, (KIGAKI)3-NH2, that has no amphipathic character as an alpha-helix but can form a highly amphipathic beta-sheet. When bound to lipids, (KIGAKI)3-NH2 did indeed form a beta-sheet struc...

Crystalline complexes of S-tert-butylisothiuronium perchlorate ( t-BuSC(NH2),C104) and 18-crown-6 (18C6) and 1,3-xylyl-18-crown-5 (1,3X18C5) with a 1:l stoichiometry were obtained via extraction. X-ray diffraction analysis showed that in the solid state the guest molecule is coordinated via one of the two NH, groups to the crown ether. The second NH2 group is bound to the anion. 'H NMR spectros...

Reactions of silver(I) salts with 4-amino-4H-1,2,4-triazole (4-NH2-tz) in a 1 : 1 molar ratio yield four new silver adducts, namely [Ag(4-NH2-tz)](CF3SO3) (1), [Ag(4-NH2-tz)1.75](ClO4) (2), [Ag(4NH2-tz)1.75](BF4) (3) and [Ag(4-NH2-tz)1.75](NO3) (4). X-Ray analysis shows that 1 exhibits a 3D cationic [Ag(4-NH2-tz)] metal-organic framework of srs topology; 2, 3 and 4 are isostructural and display...

A novel synthetic hexapeptide (SFKLRY-NH2) that displays angiogenic activity has been identified by positional scanning of a synthetic peptide combinatorial library (PS-SPCL). This study was carried out to investigate the irritation of the SFKLRY-NH2 on the skin. The tests were performed on the basis of Korea Food and Drug Administration (KFDA) guidelines. In results, cell toxicity is not appea...

Defensin from a beetle, Allomyrina dichotoma, is known to have anti-bacterial activity against Gram-positive bacteria. This peptide, which comprises 43 amino acid residues, was effective against methicillin-resistant Staphylococcus aureus. We identified the active site of beetle defensin by measuring anti-bacterial activity against S. aureus of 64 overlapping 12-mer peptides with either a free ...

8-Aminoadenosine (8-NH2-Ado), a ribosyl nucleoside analog, in preclinical models of multiple myeloma inhibits phosphorylation of proteins in multiple growth and survival pathways, including Akt. Given that Akt controls the activity of mammalian target of rapamycin (mTOR), we hypothesized that 8-NH2-Ado would be active in mantle cell lymphoma (MCL), a hematological malignancy clinically responsi...