A simple model for papilloma formation is used to analyze data from a mouse skin-painting experiment performed with NMRI mice. The results suggest that one of two conclusions may be drawn: Either the model fails to properly describe the growth behavior of papilloma cells or the model suggests that papilloma cells do not have growth advantage over normal cells, even during promotion.

UNLABELLED In the present study, the effects of pregnant NMRI mice restraint stress on the responsibility of their children to the behavioral properties of morphine, sulpiride and dextromethorphan were investigated in the F2 generation. TWENTY FOUR PREGNANT NMRI FEMALE MICE (W 25 g) were divided into the experimental and control groups (n = 12/group). Animals in the experimental group were ke...

Infertility is a relatively common problem among couples, and Gossypol, a yellowish pigment detected in cottonseed, is one cause. Adult NMRI mice (25-35 gr) were used in this study. The animals were kept in standard conditions with a dark and light cycle of 12:12, controlled humidity and temperature, food and water were available adlibitium. Gossypol was dissolved in ethanol and diluted by sunf...

The spatial correlation of nuclear magnetic resonance imaging (NMRI) and cerebral blood flow (CBF) may improve our ability to identify ischemic brain lesions and may provide further insight into the pathophysiology of early cerebral ischemia. Eleven pentobarbital-anesthetized adult cats underwent exposure of the common carotid arteries bilaterally and the right middle cerebral artery through a ...

Introduction: Morphine withdrawal syndrome is mediated via several central and peripheral neurological pathways. In the present study we investigated the role of N-methyl-D aspartic acid (NMDA) glutamate receptor on naloxone-induced withdrawal syndrome in morphine-conditioned mice. Materials and Methods: We designed two separate experiments. In experiment one, 30 male NMRI mice were divide...

Manifest diabetes, but also conditions of increased insulin resistance such as pregnancy or obesity can lead to islet architecture remodeling. The contributing mechanisms are poorly understood the consequences altered cell arrangement. For quantification different types frequency cell-cell contacts within islets, approaches exist. However, few methods available characterize distribution in a st...

BACKGROUND Erufosine is a promising anticancer drug that increases the efficacy of radiotherapy in glioblastoma cell lines in vitro. Moreover, treatment of nude mice with repeated intraperitoneal or subcutaneous injections of Erufosine is well tolerated and yields drug concentrations in the brain tissue that are higher than the concentrations required for cytotoxic drug effects on glioblastoma ...