Target Audience: Researchers or clinicians with an interest in diffusion imaging as applied to a preterm neonatal cohort. Introduction/Purpose: The human brain undergoes radical transformation late in gestation and cortical folding occurs largely during this period. In the cortex, radial glial cells act as scaffolding for neural migration, which has been imaged using the diffusion tensor model....

Recent technological progress in the multiband echo planer imaging (MB EPI) technique enables accelerated MR diffusion weighted imaging (DWI) and allows whole brain, multi-b-value diffusion imaging to be acquired within a clinically feasible time. However, its applications at 7 T have been limited due to B1 field inhomogeneity and increased susceptibility artifact. It is an ongoing debate wheth...

Diffusion-weighted magnetic resonance imaging (DWI) is undergoing constant evolution with the ambitious goal of developing in-vivo histology brain. A recent methodological advancement Neurite Orientation Dispersion and Density Imaging (NODDI), a histologically validated multi-compartment model to yield microstructural features brain tissue such as geometric complexity neurite packing density, w...

Background Several studies have suggested that advanced diffusion MRI (dMRI) measures derived through the analytic techniques of kurtosis imaging (DKI) and neurite orientation density dispersion (NODDI) might provide better sensitivity to predict progression Alzheimer’s disease (AD) when compared conventional single tensor imaging. Two popular simultaneous multislice (SMS) sequences, namely Dis...