Pulmonary nodules are soft tissue masses present in the lung that can be seen in thoracic CT images. When the size of the nodules is large, immediate attention is required. Automatic detection of these large nodules would be appreciated by the medical professionals as it reduces labor and time. The lung nodules are usually extracted through image processing and classification techniques. In thi...

OBJECTIVE Our objective was to evaluate the performance of a computer-aided detection (CAD) system for pulmonary nodule detection using low-dose screening CT images. MATERIALS AND METHODS One hundred fifty consecutive low-dose screening CT examinations were independently evaluated by a radiologist and a CAD pulmonary nodule detection system (R2 Technology) designed to identify nodules larger ...

PURPOSE This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. METHODS A retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soonchunhyang University Hospital, Korea, between May 2003 and February 2013. The average age at diag...

Absence of Kupffer cells in rat liver hyperplastic nodules induced by a chemical carcinogen was demonstrated by intravenous injection of indian ink. Hyperplastic nodules appeared 4 weeks after diethylnitrosamine (DEN) was administered, and the nodules continued growing and became eosinophilic hyperplastic nodules after 5 to 6 weeks. After intravenous injection of indian ink, hyperplastic nodule...

We intended to compare gray-scale vs. color Doppler ultrasound findings in cold thyroid nodules. Sixty-four patients with cold thyroid nodules for whom the presumptive diagnosis of malignancy (based on isotope scan study) had been made were consecutively included. They underwent gray-scale and color Doppler sonography studies. Based on histopathologic examination of surgically removed nodules, ...

In computed tomographic lung cancer screening, both solid and ground glass nodules are regularly encountered. Ground glass nodules may or may not have a solid component and it has been shown that they have a much higher chance of being malignant in comparison to solid nodules. Computer-aided detection (CAD) systems designed for solid nodules perform poorly on detection of ground glass nodules, ...

Low-dose computed tomography (CT) screening for lung cancer can reduce lung cancer mortality, but overdiagnosis, false positives and invasive procedures for benign nodules are worrying. We evaluated the utility of positron emission tomography (PET)-CT in characterising indeterminate screening-detected lung nodules. 383 nodules, examined by PET-CT over the first 6 years of the COSMOS (Continuous...

A 45-year-old female presented with symptoms of hyperthyroidism and hot nodules in the right lobe, which was diagnosed as nodular goiter by fine-needle aspiration. An anomalous thyroidectomy and difficult dissection with multiple rotations were performed around the trachea. As a remark, the pathology confirmed the presence of goiter with modular nodules (Figure 1). A macroscopic photograph show...

Fluorescein-isothiocyanate dextran (FITC-dextran), a dye confined to the vascular space, was infused via the hepatic artery and portal vein into perfused livers from fed rats treated with diethylnitrosamine for 4 to 5 months. Fluorescence due to FITC-dextran was detected with fiberoptic microlight guides placed on surface nodules of about 5 mm in diameter. Nodules were categorized into groups w...