Impaired fatty acid metabolism has been implied in a number of diseased states such as multiple sclerosis, sudden cardiac death, insulin resistance, atherosclerosis and hypertension (Blaak, 2003; Oram & Bornfeldt, 2004; Pilz et al., 2007; Sarafidis & Bakris, 2007; Hon et al., 2009a, 2009b). The fatty acid status may be assessed in plasma, platelets, red blood cells, white blood cells and brain ...

Bovine heart cytochrome-c oxidase was reconstituted in liposomes (asolectin) and the activity measured in the presence and absence of uncoupler at increasing concentrations of non-esterified fatty acids. Palmitic and stearic acids resulted in a decrease of about 40% in the respiratory control ratio at a concentration of 1 microM, when measured using a spectrophotometric procedure but not with a...

The physiological, endocrine and biochemical alterations which occur in the lactating rat to allow direction of the nutrients (glucose, amino acids, non-esterified fatty acids, triacylglycerols) to the lactating gland are described. In addition, the short-term changes in the rate of synthesis of milk constituents and the mechanisms whereby they occur are discussed.

We hypothesized that fatty acids at the sn-2 position of chylomicron triacylglycerol are preferentially released into the venous plasma (rather than being taken up and stored in the adipocytes) after hydrolysis by lipoprotein lipase (EC 3.1.1.34) in adipose tissue. Arteriovenous differences across adipose tissue were studied in eight healthy subjects on two occasions for 6 h after ingestion of ...

HOLLENBERG, C. H., AND A. ANGEL. Relation of fatty acid structure to release and esterijication of free fatty acids. Am. J. Physiol. 205(5): 909-912. I g63.-After incubation of rat adipose tissue with corticotrophin in buffer-albumin, the composition of the free fatty acids (FFA) in the tissue and in the medium was determined; the medium contained proportionately more myristic, palmitoleic, lin...

BACKGROUND Ligands of peroxisome-proliferator activated receptors (PPARs), such as non-esterified fatty acids (NEFAs), induce expression of angiopoietin-like protein 4 (ANGPTL4). Recently ANGPTL4 has been reported to be a mediator of intracellular adipose lipolysis induced by glucocorticoids. OBJECTIVE To determine the concentrations of ANGPTL4 in cord serum of neonates born by spontaneous va...

The effects of Greyhound racing on plasma insulin, glucagon and non-esterified fatty acid have not been extensively studied. We sought to examine the effects of exercise in 19 greyhounds trialed over 400 meters on serum biochemistry, osmolality, nonessential fatty acids, and the major glucoregulatory hormones insulin and glucagon, before and after racing. Due to the non-traditional dietary patt...

The relationship between intestinal bile acids and the micellar solubilization of lipids was studied by determining micellar bile acids and distribution of cholesterol and 0-sitosterol, their esters, and of hydrolysis products of triglycerides (labeled with H-tristearate), free fatty acids, monoglycerides and diglycerides between the micellar and oil phases of the intestinal contents for 1% h a...