Background: Micro RNAs (miRNAs) are a pivotal part of non-protein-coding endogenous small RNA molecules that regulate the genes involved in plant growth and development, and respond to biotic and abiotic environmental stresses posttranscriptionally.Objective: In the present study, we report the results of a systemic search for identifi cation of new miRNAs in B. rapa using homology-based ...

Recent advances in high-throughput sequencing technology have identified the transcription of a much larger portion of the genome than previously anticipated. Especially in the context of cancer it has become clear that aberrant transcription of both protein-coding and long non-coding RNAs (lncRNAs) are frequent events. The current dogma of RNA function describes mRNA to be responsible for the ...

Abstract Long, non-coding (Inc) RNAs emerge as crucial regulators of gene expression. Their ability to interact with DNA and protein mediates the recruitment defined chromosomal loci. LncRNAs are particularly abundant in brain tissues where they involved cell specification. We described a novel lncRNA, RUS (RNA upstream Slitrk3), which interacts epigenetic contributes shaping expression program...

Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces the research on the structure and functional interactions of these RNA gene sequences. We mine the evolutionary sequence record to derive precise information about the function and structure of RNAs and RNA-protein complexes. As in protein structure prediction, we use maximum entropy global probability mode...

A variety of RNA molecules have been found in the last two decades with a wide range of biological functions beyond the traditional roles of the well-known coding RNA (messenger RNA or mRNA) and non-coding RNA (ribosomal and transfer RNA). Over twenty years ago, the discovery of the catalytic properties of the RNA subunit of the ribonuclease P and the self-splicing activity of group I introns s...

Chronic Lymphocytic Leukemia (CLL) is one kind of blood cancer that has a very heterogeneous biological background, which results in diverse stages the CLL and complex treatment strategies. However, small part tumor may disappear without receiving any treatment. This condition known as “spontaneous regression” occurs result poorly investigated mechanism. Exposing underlying causes this can lead...