Primary non-secretory Plasma cell leukemiaisa rare diagnosis with only few cases reported so far. Here we report a case of a non secretory Plasma cell leukemia diagnosed on flow cytometry, as atypical morphology and negative serum and urine protein electrophoresis made it difficult to come to a conclusive diagnosis based on morphology.

multiple myeloma (mm) is characterized by progressive proliferation of malignant plasma cells, usually initiating in the bone marrow. mm can affect any organ; a total of 7 - 18% of patients with mm demonstrate extramedullary involvement at diagnosis. non-secretory multiple myeloma (nsmm) is a rare variant that accounts for 1 - 5% of all cases of multiple myeloma. the disease is characterized by...

background: inverse relationship between helminths infection and immune-mediated diseases has inspired researchers to investigate therapeutic potential of helminths in allergic asthma. helminth unique ability to induce immunoregulatory responses has already been documented in several experimental studies. this study was designed to investigate whether excretory/secretory (es) and somatic produc...

Pituitary adenomas are common benign tumors that may or may not produce hormones that are rarely malignant. Those that do not generate hormones are considered non-functioning or non-secretory. Non-secretory pituitary adenomas are defined as tumors of the pituitary gland that lack the characteristic of hormone hypersecretion and account for 18 to31% of all surgically treated pituitary adenomas [...

abstract background: the children with middle ear effusion need repeated re-tympanostomies. adenoidectomy is an effective surgical intervention in the management of chronic otitis media with effusion in conjunction with in-sertion of tympanostomy tubes (tts). to find out whether tts in different positions decrease the rate of re-tympanostomies study was done. methods: the present study retrospe...

background: recent attention has focused on the expression of integrin molecules within the endometrium, and their relation to infertility. objective: the present prospective study was undertaken to determine whether the endometrium of women with unexplained infertility differs in the expression of very late activation antigens (vla) from the endometrium of normal fertile women. methods: thirty...

background: sparganosis is caused by the invasion of spirometra sparganum into various tissues/organs. subcutaneous sparganosis can be diagnosed by biopsy , while visceral/cerebral sparganosis is not easy to be diagnosed. the diagnosis de-pends largely on the detection of specific anti-sparganum antibodies. t he specific-ity of the elisa could be increased by using s. mansoni sparganum excretor...

The theme of this dissertation is the mode of presentation, assessment and management of six patients with tumours of the pituitary gland. Such tumours may be secretory or non-secretory. Typically secretory tumours present with endocrine abnormalities due to hypersecretion of a particular hormone, while nonsecretory tumours present with symptoms caused by the expansion of the lesion in the pitu...